Refractive Error, Ocular Biometry, and Lens Opalescence in an Adult Population: The Los Angeles Latino Eye Study

Shufelt, Chrisandra; Fraser‐Bell, Samantha; Ying-Lai, Mei; Torres, Mina; Varma, Rohit

doi:10.1167/iovs.05-0435

Cited by 183 publications

(211 citation statements)

References 23 publications

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“…For example, near work was more intensive in the younger age group, which is a factor increasing AL probably due to a defocus-induced disturbance of emmetropisation [43]. However, the Los Angeles Latino Eye Study did not reveal an age-related AL difference based on a population of 5,588 participants over a period of 40 years [44]. Meanwhile, it is well agreed that women tend to have a shorter AL [34,35], partly explained by stature [45].…”

Section: Axial Lengthmentioning

confidence: 99%

Axial Length of Myopia: A Review of Current Research

Wang

Butterworth²,

Malecaze³

et al. 2010

Ophthalmologica

163

119

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Myopia, or nearsightedness, is a worldwide common type of refractive error. It is a non-life-threatening disorder with huge social and economic consequences due to its increasing prevalence. Axial length (AL) is the primary determinant of non-syndromic myopia. It is a parameter representing the combination of anterior chamber depth, lens thickness and vitreous chamber depth of the eye. AL can also be treated as an endophenotype of myopia and may provide extra advantages in the investigation of its genetic basis. The study of AL will not only identify the determinants of eye elongation, but also provide aetiological evidence for myopia. The purpose of this review is to outline the current state of AL research. Epidemiological evidence, genetic determinants, the relationship with other eye components and relative animal models of AL are summarised.

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Section: Axial Lengthmentioning

confidence: 99%

Axial Length of Myopia: A Review of Current Research

Wang

Butterworth²,

Malecaze³

et al. 2010

Ophthalmologica

163

119

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“…ACD decreases with age in all populations and is shallowest in the Inuit 2 and deepest in the Caucasian Latino population. 25 (Data has been assimilated as an average of agespecific ACD and adapted from Johnson and Foster. 26 Singapore, Lim et al 19 found that compared with fellow eyes, AACG-affected eyes had significantly shallower ACDs, more anterior lens position, and less cortical cataract.…”

Section: Recently Foundmentioning

confidence: 99%

Risk factors for early angle-closure disease in a Burmese population: the Meiktila Eye Study

Casson

Marshall

Newland

et al. 2008

Eye

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Purpose To determine risk factors for early angle-closure disease (AD) in a Burmese population. Methods A cross-sectional, population-based survey of the inhabitants, 40 years of age and over, from villages in the Meiktila District was performed; 2481 eligible participants were identified, 2076 participated in the study, and 2050 could be categorized as having early AD (defined by the presence of so-called occludable angles (o90 degrees of posterior trabecular meshwork visible on gonioscopy), but without glaucomatous optic neuropathy). The ophthalmic examination included Snellen visual acuity, slit-lamp examination, tonometry, gonioscopy, biometry, and dilated stereoscopic fundus examination. Results The mean axial length (AL) and anterior chamber depth (ACD) in those with occludable angles were 21.9 and 2.60 mm, respectively; in those with non-occludable angles, the corresponding lengths were 22.74 and 2.84 mm, respectively (Po0.001 for both comparisons). In the univariate analyses, age, female gender, nuclear and cortical cataract, steeper corneal curvature, more anterior lens position, and myopia were also significantly associated with occludability. In the multivariate analysis, age, AL, ACD, and nuclear cataract were significantly associated with occludability. Conclusion In this Burmese population, those with occludable angles had significantly shorter ALs, ACDs, and thicker lenses than those without occludable angles. In multivariate analysis, increasing age, decreasing AL, decreasing ACD, and nuclear cataract were significant predictors of early AD. The presence of nuclear cataract per se should raise clinical suspicion of the possibility of AD in this population.

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“…In-depth knowledge of ocular biometric parameters is therefore required in understanding the risk factors and determinants of ammetropia [8][9][10][11] and in formulating appropriate preventative and treatment strategies. The most important factor in the refractive errors is relationship to the ocular components [9].…”

Section: Research Articlementioning

confidence: 99%

Central Corneal Thickness: Important Considerate in Ophthalmic Clinic

Thakur¹

2017

Austin J Clin Ophthalmol

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Results:The mean SE, KM and CCT of the patients under the study were (-) 0.47 ± 2.26,43.79 ± 1.18D and 528.41 ± 19.1µm. Mean CCT was higher in age group C (46 to 60 yrs) than other groups (p = 0.008) but no impact was found on increasing age after regression analysis. CCT was not affected by gender (p = 0.168). Mean CCT for Myopic was found to be 522.87±18.03µm which was lower compared to in Hypermetropic (536.39 ±17.753µm) (p = <0.001). There was a positive correlation between CCT and SE (r = 0.520, p = <0.001). However KM showed negative correlation with CCT (r = -0.288, p = <0.001). Conclusion:From above study we concluded that CCT was related to age, refractive status and keratometry but not to sex.

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Refractive Error, Ocular Biometry, and Lens Opalescence in an Adult Population: The Los Angeles Latino Eye Study

Abstract: Age- and gender-related differences in ocular biometric, refractive error, and NOP measurements are present in adult Latinos. While the relative contribution of NOP in determining refractive error is small, it is greater in older persons compared to younger individuals.

Cited by 183 publications

References 23 publications

Axial Length of Myopia: A Review of Current Research

Axial Length of Myopia: A Review of Current Research

Risk factors for early angle-closure disease in a Burmese population: the Meiktila Eye Study

Central Corneal Thickness: Important Considerate in Ophthalmic Clinic

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