Refolding of protein unfolded by gemini surfactants using β-cyclodextrin and sodium dodecyl sulfate in aqueous medium: Study on role of spacer chain of surfactants

Refolding of denatured gold nanoparticles-conjugated bovine serum albumin through formation of catanions between gemini surfactant and sodium dodecyl sulphate

“…Our group also has reported before the formation of various structures in a solution containing SDS and different gemini surfactants. 4 There are many other groups who have reported the formation of catanions/mixed assemblies like rod-like micelles, vesicles, lamellar micelles etc. even in the absence of a protein.…”

“…These catanionic micelles often behave as refolding agents for unfolded proteins. Kumari et al 4 have investigated the formation of the mixed micellar systems between gemini surfactants, 12- n -12,2Br − ( n = 3, 6, 8, 12) and SDS in order to refold back the gemini-induced denatured BSA into its native conformation. When protein gets refolded, simultaneously some big particles formed in the system are aggregates of SDS and gemini surfactants.…”

“…1,2 Improper folding of protein or aggregation of protein are the preliminary causes of serious human degenerative diseases such as cancer, Alzheimer's, amyotrophic lateral sclerosis, etc. 3,4 Thus, the prevention of protein aggregation and the refolding of protein have always been attractive topics of progressing interest.…”

Designing Novel High-Performance Shale Inhibitors by Optimizing the Spacer Length of Imidazolium-Based Bola-Form Ionic Liquids

“…27,28 Besides, spacer length also affects the interaction between ILs and other materials, such as surfactants, protein, and nematic liquid crystal. 29,30 In another report of Yang's group, vinylimidazolium-based ionic liquids with a shorter chain showed better inhibition performance, which was mainly attributed to the reduced water activities and decreased interlayer spacing. 31 To the best of our knowledge, there are few studies on designing high-performance bola-form shale inhibitors by optimizing their spacer lengths.…”

“…Moreover, the spacer length of the bola-form inhibitor should be optimized to achieve optimal inhibitive performance. In many previous studies, researchers have reported that the spacer length exerted great influence on the properties of ILs, such as surface activity, critical micelle concentration (CMC), microstructure, and growth of micelles. , Besides, spacer length also affects the interaction between ILs and other materials, such as surfactants, protein, and nematic liquid crystal. , In another report of Yang’s group, vinylimidazolium-based ionic liquids with a shorter chain showed better inhibition performance, which was mainly attributed to the reduced water activities and decreased interlayer spacing . To the best of our knowledge, there are few studies on designing high-performance bola-form shale inhibitors by optimizing their spacer lengths.…”