Reflexive and voluntary saccadic eye movements as biomarker of Huntington’s Disease
Natalia Grabska,
Magdalena Wójcik-Pędziwiatr,
Jarosław Sławek
et al.
Abstract:Introduction. Subtle abnormalities in the preclinical stage of Huntington's Disease (HD) can be detected using saccadic eye movement assessment reflecting disease progression. This study was aimed to evaluate abnormalities in saccade parameters in asymptomatic carriers and symptomatic HD patients at various stages of HD.
Material and methods.The study enrolled 104 participants, including 14 asymptomatic carriers of HTT mutations, 44 symptomatic HD patients, and 46 control subjects. HD severity was measured usi… Show more
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