Reflex strategy to ensure accurate total testosterone results from consumer initiated, self-collected capillary samples

Naranjo, Anissa R.; Krasowski, Matthew D.; Hamdan, Amal; O’Connor, Kristin; Carter, Claire; Chen, Joyce; Greene, Dina N.

doi:10.1016/j.cca.2024.119676

Clinica Chimica Acta

2024

DOI: 10.1016/j.cca.2024.119676

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Reflex strategy to ensure accurate total testosterone results from consumer initiated, self-collected capillary samples

Anissa R. Naranjo,

Matthew D. Krasowski,

Amal Hamdan

et al.

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Cited by 1 publication

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Point-of-care testing: state-of-the art and perspectives

Plebani,

Nichols,

Luppa

et al. 2024

Clinical Chemistry and Laboratory Medicine (CCLM)

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Point-of-care testing (POCT) is becoming an increasingly popular way to perform laboratory tests closer to the patient. This option has several recognized advantages, such as accessibility, portability, speed, convenience, ease of use, ever-growing test panels, lower cumulative healthcare costs when used within appropriate clinical pathways, better patient empowerment and engagement, and reduction of certain pre-analytical errors, especially those related to specimen transportation. On the other hand, POCT also poses some limitations and risks, namely the risk of lower accuracy and reliability compared to traditional laboratory tests, quality control and connectivity issues, high dependence on operators (with varying levels of expertise or training), challenges related to patient data management, higher costs per individual test, regulatory and compliance issues such as the need for appropriate validation prior to clinical use (especially for rapid diagnostic tests; RDTs), as well as additional preanalytical sources of error that may remain undetected in this type of testing, which is usually based on whole blood samples (i.e., presence of interfering substances, clotting, hemolysis, etc.). There is no doubt that POCT is a breakthrough innovation in laboratory medicine, but the discussion on its appropriate use requires further debate and initiatives. This collective opinion paper, composed of abstracts of the lectures presented at the two-day expert meeting “Point-Of-Care-Testing: State of the Art and Perspective” (Venice, April 4–5, 2024), aims to provide a thoughtful overview of the state-of-the-art in POCT, its current applications, advantages and potential limitations, as well as some interesting reflections on the future perspectives of this particular field of laboratory medicine.

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Point-of-care testing: state-of-the art and perspectives

Plebani,

Nichols,

Luppa

et al. 2024

Clinical Chemistry and Laboratory Medicine (CCLM)

View full text Add to dashboard Cite

show abstract

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Reflex strategy to ensure accurate total testosterone results from consumer initiated, self-collected capillary samples

Cited by 1 publication

References 21 publications

Point-of-care testing: state-of-the art and perspectives

Point-of-care testing: state-of-the art and perspectives

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