Abstract:Reflection-type photoplethysmography (PPG) pulse sensors are widely used in consumer markets to measure cardiovascular signals. Different from off-chip package solutions in which the light-emitting diode (LED) and photodetector (PD) are in separate chips, a GaN integrated optoelectronic chip with a novel ring structure is proposed to realize a PPG pulse sensor. The integrated optoelectronic chip consists of two multiple-quantum well (MQW) diodes. For higher sensitivities, the central and peripheral MQW diodes … Show more
“…Precise evaluation of arterial pulse rate and the behavior of pulse patterns can identify early signs of cardiovascular diseases like atherosclerosis and arterial stiffness . Piezoresistive, piezoelectric, and reflective sensors are often employed for fabricating wearable pulse monitors, among which the piezoresistive sensors are the cheapest. , However, most of the reported piezoresistive sensors cannot precisely transduce the variations occurring in a single pulse during the systolic and diastolic cycles. The fabricated sensor was evaluated in light of these challenges.…”
Silver nanoparticles of average size 12–13 nm
were successfully
decorated on the surface of multiwalled carbon nanotubes (MWCNTs)
through a scalable wet chemical method without altering the structure
of the MWCNTs. Employing this Ag@MWCNT, a multifunctional room-temperature
curable conductive ink was developed, with PEDOT:PSS as the conductive
binder. Screen printing of the ink could yield conductive planar traces
with a 9.5 μm thickness and a conductivity of 28.99 S/cm, minimal
surface roughness, and good adhesion on Mylar and Kapton. The versatility
of the ink for developing functional elements for printed electronics
was demonstrated by fabricating prototypes of a wearable strain sensor,
a smart glove, a wearable heater, and a wearable breath sensor. The
printed strain sensor exhibited a massive sensing range for wearable
applications, including an impressive 1332% normalized resistance
change under a maximum stretchability of 23% with superior cyclic
stability up to 10 000 cycles. The sensor also exhibited an
impeccable gauge factor of 142 for a 5% strain (59 for 23%). Furthermore,
the sensor was integrated into a smart glove that could flawlessly
replicate a human finger’s gestures with a minimal response
time of 225–370 ms. Piezoresistive vibration sensors were also
fabricated by printing the ink on Mylar, which was employed to fabricate
a smart mask and a smart wearable patch to monitor variations in human
respiratory and pulmonary cycles. Finally, an energy-efficient flexible
heater was fabricated using the developed ink. The heater could generate
a uniform temperature distribution of 130 °C at the expense of
only 393 mW/cm2 and require a minimum response time of
20 s. Thus, the unique formulation of Ag@MWCNT ink proved suitable
for versatile devices for future wearable applications.
“…Precise evaluation of arterial pulse rate and the behavior of pulse patterns can identify early signs of cardiovascular diseases like atherosclerosis and arterial stiffness . Piezoresistive, piezoelectric, and reflective sensors are often employed for fabricating wearable pulse monitors, among which the piezoresistive sensors are the cheapest. , However, most of the reported piezoresistive sensors cannot precisely transduce the variations occurring in a single pulse during the systolic and diastolic cycles. The fabricated sensor was evaluated in light of these challenges.…”
Silver nanoparticles of average size 12–13 nm
were successfully
decorated on the surface of multiwalled carbon nanotubes (MWCNTs)
through a scalable wet chemical method without altering the structure
of the MWCNTs. Employing this Ag@MWCNT, a multifunctional room-temperature
curable conductive ink was developed, with PEDOT:PSS as the conductive
binder. Screen printing of the ink could yield conductive planar traces
with a 9.5 μm thickness and a conductivity of 28.99 S/cm, minimal
surface roughness, and good adhesion on Mylar and Kapton. The versatility
of the ink for developing functional elements for printed electronics
was demonstrated by fabricating prototypes of a wearable strain sensor,
a smart glove, a wearable heater, and a wearable breath sensor. The
printed strain sensor exhibited a massive sensing range for wearable
applications, including an impressive 1332% normalized resistance
change under a maximum stretchability of 23% with superior cyclic
stability up to 10 000 cycles. The sensor also exhibited an
impeccable gauge factor of 142 for a 5% strain (59 for 23%). Furthermore,
the sensor was integrated into a smart glove that could flawlessly
replicate a human finger’s gestures with a minimal response
time of 225–370 ms. Piezoresistive vibration sensors were also
fabricated by printing the ink on Mylar, which was employed to fabricate
a smart mask and a smart wearable patch to monitor variations in human
respiratory and pulmonary cycles. Finally, an energy-efficient flexible
heater was fabricated using the developed ink. The heater could generate
a uniform temperature distribution of 130 °C at the expense of
only 393 mW/cm2 and require a minimum response time of
20 s. Thus, the unique formulation of Ag@MWCNT ink proved suitable
for versatile devices for future wearable applications.
“…PPG is a fast and noninvasive spectroscopic measurement technique 9 used to detect changes of the blood volume in peripheral circulation 10 either in reflection or transmission mode. 11 The acquired spectra show a constant offset, i.e., a direct current (DC) component, which is caused by the absorption and scattering of the tissue under investigation and the constant blood volume inside the blood vessels. A time-variant alternating current component resulting from the increasing and decreasing blood volume during systole and diastole, corresponding to the desired measurement signal, is superimposed on this DC background.…”
Section: Introductionmentioning
confidence: 99%
“…A time-variant alternating current component resulting from the increasing and decreasing blood volume during systole and diastole, corresponding to the desired measurement signal, is superimposed on this DC background. 11 – 13 Using the PPG approach, a variety of clinical parameters can be determined, including the blood oxygen saturation, heart rate, and blood pressure. 14 , 15 Furthermore, a PPG measurement is able to assess arterial diseases, as well as arterial compliance and aging, 16 , 17 which makes it a highly useful tool in medical diagnostics.…”
.
Significance
For the development and routine characterization of optical devices used in medicine, tissue-equivalent phantoms mimicking a broad spectrum of human skin properties are indispensable.
Aim
Our work aims to develop a tissue-equivalent phantom suitable for photoplethysmography applications. The phantom includes the optical and mechanical properties of the three uppermost human skin layers (dermis, epidermis, and hypodermis, each containing different types of blood vessels) plus the ability to mimic pulsation.
Approach
While the mechanical properties of the polydimethylsiloxane base material are adjusted by different mixing ratios of a base and curing agent, the optical properties are tuned by adding titanium dioxide particles, India ink, and synthetic melanin in different concentrations. The layered structure of the phantom is realized using a doctor blade technique, and blood vessels are fabricated using molding wires of different diameters. The tissue-mimicking phantom is then integrated into an artificial circulatory system employing piezo-actuated double diaphragm pumps for testing.
Results
The optical and mechanical properties of human skin were successfully replicated. The diameter of the artificial blood vessels is linearly dependent on pump actuation, and the time-dependent expansion profile of real pulse forms were mimicked.
Conclusions
A tissue equivalent phantom suitable for the
ex-vivo
testing of opto-medical devices was demonstrated.
“…Volumetric pulse sensors utilize photoplethysmography (PPG) to measure the changes of blood vessel volume to characterize the pulse fluctuations. Yan et al [ 16 ] proposed a GaN integrated optoelectronic device using a ring-shaped structure to achieve pulse detection when using fingertip touching; however, this device was susceptible to the interferences from external light. In contrast, pressure pulse sensors can detect the pressure waves from pulse beating and characterize pulse fluctuations, which corresponds with the ‘Ju’, ‘An’, and ‘Xun’ methods of pulse diagnosis based on Chinese traditional medicine.…”
Wearable pulse detection devices can be used for daily human healthcare monitoring; however, the relatively poor flexibility and low sensitivity of the pulse detection devices are hindering the scrutiny of pulse information during pulse diagnosis of different pulse positions. This paper developed a novel and wearable pulse detection device based on three flexible pressure sensors using synthetic graphene and silver composites as the pressure sensing material. The structural design of the pulse detection device is firstly presented; the core component of pressure sensors is using the sawtooth protrusions to convert pressure induced by radial pulse vibrations into localized deformation of graphene composites. The fabricated pulse detection device is characterized by high pressure sensing performance, including relatively high sensitivity (8.65% kPa−1), broad sensing range (12 kPa), and good dynamic response with a response time of about 100 ms. Then, the pulse detection device is worn on a human wrist to detect the pulses from three pulse positions, namely, ‘Cun’, ‘Guan’, and ‘Chi’, and the results demonstrated the capability of using our device to detect pulse signals. The physical conditions of the subject, such as arterial stiffness index, can be further analyzed through the characteristics of the acquired pulse signals, demonstrating the potential application of using wearable pulse detection devices for human health monitoring.
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