Reflectance Confocal Microscopy in Oncological Dermatology

Application of 3-dimensional reflectance confocal microscopy: Melanocytic proliferations as three-dimensional models

“…When MSDS is present, asymmetric pigmentation ( partially edged or nonedged dermal papillae) may be noted around dermal papillae. 3 This phenomenon may be due to nonuniform melanin transfer or melanoma cell population density differences. The dermoepidermal junction also frequently becomes flattened in malignant tumors.…”

“…To the Editor: In cutaneous melanomas, the coloration or degree of pigmentation of the melanoma is variable and may be associated with histologic features and prognosis. [1][2][3] The effect of the degree of pigmentation on the occurrence and site of first metastasis is unknown. We investigated the prognostic factors for acral melanomas and whether the degree of pigmentation of acral melanoma was correlated with the first metastasis site.…”