Refinement of the Nanoparticle Emission Assessment Technique into the Nanomaterial Exposure Assessment Technique (NEAT 2.0)

Eastlake, Adrienne; Beaucham, Catherine; Martinez, Kenneth; Dahm, Matthew M.; Sparks, Christopher; Hodson, Laura; Geraci, Charles L.

doi:10.1080/15459624.2016.1167278

Cited by 58 publications

(32 citation statements)

References 29 publications

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“…The Field Studies Team observed work practices used during the production or use of ENMs and the use of PPE, including respiratory protection (if any), during each of the 11 evaluations 1,16) . It is also important to consider the non-nanomaterial chemicals that may be used to prepare or process ENM-containing slurries 1) .…”

Section: Personal Protective Equipmentmentioning

confidence: 99%

“…This document also grouped sampling results from several NTRC on-site studies. With increased understanding of nanomaterial uses, controls, and sampling techniques, NIOSH issued NEAT 2.0 1) , an updated version that is currently used as a framework for NIOSH/NTRC Field Studies Team evaluations. The original NEAT made use of direct reading instruments (DRIs) to identify workplace tasks associated with nanoparticle emissions.…”

Section: Introductionmentioning

confidence: 99%

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Exposures during wet production and use processes of nanomaterials: a summary of 11 worksite evaluations

2020

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From 2011-2015, the National Institute for Occupational Safety and Health Nanotechnology Field Studies Team conducted 11 evaluations at worksites that either produced engineered nanomaterials (ENMs) via a wet process or used ENMs in a wetted, suspended, or slurry form. Wet handling or processing of ENMs reduces potential exposure compared to dry handling or processing; however, air sampling data indicated exposures may still occur. Information was gathered about each company, production processes, ENMs of interest, and control measures. Exposure assessments included air sampling using filter media, surface wipe sampling, and real-time particle counting by direct-reading instruments. Electron microscopy analysis of air filters confirmed the presence of ENMs of interest (10 of 11 sites). When a method was available, chemical analysis of filters was also used to detect the presence of ENMs (nine of 11 sites). Wipe samples were collected at four of the 11 sites, and, in each case, confirmed the presence of ENMs on surfaces. Direct-reading data showed potential nanomaterial emissions (nine of 11 sites). Engineering controls included fume hoods, cleanrooms, and enclosed processes. Personal protective equipment was required during all 11 evaluations. Recommendations to address potential exposures were provided to each company following the hierarchy of controls.

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Section: Personal Protective Equipmentmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Exposures during wet production and use processes of nanomaterials: a summary of 11 worksite evaluations

2020

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“…Researchers had assessed the problem of selecting the suitable method for the preparation of nano particles [32]. Nano sensors contribute to the specificity, sensitivity, and performance of the methods and improved by using nano materials for their construction [23,33]. The nanotechnology based biosensor or nano biosensor technology is revolutionizing the health care industry such as the nano biosensor technology which is used in the measurement of metabolites, monitoring of diabetes forensic medicine, homeland security [34].…”

Section: Analytical Techniques Employed In Nanotechnologymentioning

confidence: 99%

A Review on Nanotechnology: Analytical Techniques Use and Applications

Bahru

Ajebe

2019

IRJPAC

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The combination of nanotechnology with molecular biology, information technology and instrumentation, is opening the door to a new industrial age. The aim of this review article is to summarize the current knowledge of nanotechnology in synthesizing, identifying and characterization of nanomaterials using analytical techniques. Physical and chemical approach synthesis of nanomaterials befalls challenges in the development of analytical techniques used to characterize them. The major techniques include: Transmission Electron Microscopy, Scanning Electron Microscopy, Atomic Force Microscopy, Dynamic Light Scattering, X ray Photoelectron Spectroscopy, X-ray Diffraction, Single Phase Inductively Coupled Plasma Mass Spectroscopy, X ray Fluorescence Spectroscopy, Auger Electron Spectroscopy, X ray Absorption Fine Structure, Capillary Electrophoretic Separations, Magnetic nano particles coupled HPLC and Dynamic light scattering. Nanomaterials have been characterized for the extensive potential applications in optics, electronics, magnetics, and catalysts; chemical sensing, biomedicine, micro reactor, and they have been applied in food, biological, environmental and pharmaceuticals uses. In spite of the extended use of nano particles in diverse consumer products, there is a great concern over the unexpected impact or effects on humans due to exposure.

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“…16 The best available guidance for exposure measurement suggests that in addition to an appropriate characterisation of particle size distribution, measurements should at least encompass an assessment of mass, but where possible also include number and/or surface area concentration. 17,18 Confronted with these limitations, it was decided that the most sensible course of action is to focus on (i) qualitative risk assessment covering all 1 In addition, input from (i) experts in the NanoSafety Cluster (NSC) community, (ii) EU institutions (e.g., ECHA), (iii) international organisations (e.g., OECD 27 ), (iv) industry initiatives (e.g., ECETOC 28,29 ), (v) European Center for Nanotoxicology (EURO-NanoTox), 54 and (vi) peerreviewed scientific literature, have been considered to ensure consistency at EU level and alignment to the stateof-the-art.…”

Section: Introductionmentioning

confidence: 99%

A methodology on how to create a real-life relevant risk profile for a given nanomaterial

Schimpel¹,

Resch²,

Flament³

et al. 2018

J. Chem. Health Saf.

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Please cite this article in press as: Schimpel, C. et al1., A methodology on how to create a real-life relevant risk profile for a given nanomaterial. J. Chem. Health Safety (2017), http://dx.doi.org/10.1016/j.jchas.2017.06.002 RESEARCH ARTICLEA methodology on how to create a real-life relevant risk profile for a given nanomaterial With large amounts of nanotoxicology studies delivering contradicting results and a complex, moving regulatory framework, potential risks surrounding nanotechnology appear complex and confusing. Many researchers and workers in different sectors are dealing with nanomaterials on a day-to-day basis, and have a requirement to define their assessment/management needs. This paper describes an industry-tailored strategy for risk assessment of nanomaterials and nano-enabled products, which builds on recent research outcomes. The approach focuses on the creation of a risk profile for a given nanomaterial (e.g., determine which materials and/or process operation pose greater risk, where these risks occur in the lifecycle, and the impact of these risks on society), using state-of-the-art safety assessment approaches/tools (ECETOC TRA, Stoffenmanager Nano and ISO/TS 12901-2:2014). The developed nanosafety strategy takes into account cross-sectoral industrial needs and includes (i) Information Gathering: Identification of nanomaterials and hazards by a demand-driven questionnaire and on-site company visits in the context of human and ecosystem exposures, considering all companies/parties/downstream users involved along the value chain; (ii) Hazard Assessment: Collection of all relevant and available information on the intrinsic properties of the substance (e.g., peer reviewed (eco)toxicological data, material safety data sheets), as well as identification of actual recommendations and benchmark limits for the different nano-objects in the scope of this projects; (iii) Exposure Assessment: Definition of industry-specific and application-specific exposure scenarios taking into account operational conditions and risk management measures; (iv) Risk Characterisation: Classification of the risk potential by making use of exposure estimation models (i.e., comparing estimated exposure levels with threshold levels); (v) Refined Risk Characterisation and Exposure Monitoring: Selection of individual exposure scenarios for exposure monitoring following the OECD Harmonized Tiered Approach to refine risk assessment; (vi) Risk Mitigation Strategies: Development of risk mitigation actions focusing on risk prevention.

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Refinement of the Nanoparticle Emission Assessment Technique into the Nanomaterial Exposure Assessment Technique (NEAT 2.0)

Cited by 58 publications

References 29 publications

Exposures during wet production and use processes of nanomaterials: a summary of 11 worksite evaluations

Exposures during wet production and use processes of nanomaterials: a summary of 11 worksite evaluations

A Review on Nanotechnology: Analytical Techniques Use and Applications

A methodology on how to create a real-life relevant risk profile for a given nanomaterial

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