Referenzwerte für die Konzentration der freien Aminosäuren im Nüchternserum von Kindern

Liappis, N; Gobien, N; Schlebusch, H.

doi:10.1055/s-2007-1025511

Klin Padiatr

1990

DOI: 10.1055/s-2007-1025511

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Referenzwerte für die Konzentration der freien Aminosäuren im Nüchternserum von Kindern

N Liappis¹,

N Gobien²,

H. Schlebusch

Abstract: Concentrations of free amino acids were determined quantitatively by ion exchange column chromatography in serum from the fasting blood of 352 (male = 177, female = 175) "healthy" infants, children and adolescents. Serum was deproteinised by 5% sulphosalicylic acid (1:1, v/v). The results -95% confidence range-are presented age-dependent (groups: up to 1 month, 1-24 months, 2-6 years, 6-10 years, 10-14 years) and sex-dependent in table 4 and 5.

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Branched chain amino acids as a parameter for catabolism in treated phenylketonuria

et al. 2004

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This study was performed to study an association between nutritional status on one hand and BCAA- and Phe-concentrations on the other hand in PKU patients free of infection. AA profiles from 70 PKU patients were measured. 9 patients (subgroup I) with elevated Phe- and BCAA-concentrations as well as 23 patients (subgroup II) with only elevated Phe-levels were included. Dietary records were obtained from both groups; low caloric intake in subgroup I was increased with Duocal or p-am ANAMIX without modifying total protein- and Phe-intake. AA profiles were controlled after 2 weeks. Additionally, we investigated AA profiles from 26 liver transplanted patients with increased carbohydrate and caloric intake as an example for anabolism. In subgroup I Phe- and Isoleu-concentrations decreased sign. After dietary intervention. Leu, Val and Tyr levels decreased not sign. Initial Phe-levels correlated negatively with protein and caloric intake. BCAA concentrations of liver transplanted patients receiving high amounts of carbohydrates were in the lower range of normal. Increased caloric intake lowered most of the elevated Phe- and BCAA- concentrations.

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Branched chain amino acids as a parameter for catabolism in treated phenylketonuria

et al. 2004

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Plasma and urine amino acid pattern in preterm infants on enteral nutrition: impact of gestational age

et al. 2009

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Plasma and urine amino acids were determined by ion-exchange chromatography in 80 healthy preterm infants divided into three groups: (1) 23 0/7-28 0/7, (2) 28 1/7-32 0/7 and (3) 32 1/7-35 0/7 weeks of gestation. Samples were collected from days 5 to 57 of life, when infants were exclusively orally fed. Infants with evidence of underlying diseases were excluded. Concentrations of most plasma amino acids increased with gestational and maturational age; urinary excretion followed an opposite course. Few amino acids depended on postnatal age. Plasma amino acids did not correlate inversely to their counterparts in urine indicating that plasma amino acids do not simply reflect kidney function. Some amino acids in blood and urine were linked to nutrient intake and body weight. Our data clearly indicate the heterogeneity of the preterm cohort; therefore, gestational age-matched reference values have to be used for diagnostic purposes in preterm infants.

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Nitrogen balance, 3-methylhistidine excretion, and plasma amino acid profile in infants after cardiac operations for congenital heart defects: The effect of early nutritional support

Chaloupecký¹,

Hučín²,

Tláskal³

et al. 1997

The Journal of Thoracic and Cardiovascular Surgery

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Referenzwerte für die Konzentration der freien Aminosäuren im Nüchternserum von Kindern

Cited by 6 publications

References 1 publication

Branched chain amino acids as a parameter for catabolism in treated phenylketonuria

Branched chain amino acids as a parameter for catabolism in treated phenylketonuria

Plasma and urine amino acid pattern in preterm infants on enteral nutrition: impact of gestational age

Nitrogen balance, 3-methylhistidine excretion, and plasma amino acid profile in infants after cardiac operations for congenital heart defects: The effect of early nutritional support

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