Referential modification strategy based on phenolic hydroxyl-containing KSA luminogens for ER-targeting probe construction

Deng, Qiyun; Ding, Keke; Li, Yin; Jiao, Yawen; Hu, Rong; Zhang, Tian; Wang, Zhiming; Tang, Ben Zhong

doi:10.1016/j.biomaterials.2022.121767

Cited by 6 publications

(4 citation statements)

References 47 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Section: Resultsmentioning

confidence: 99%

“…Therefore, it can be inferred that the increased retention of Teb@MBD nanoparticles at the leaf surface may be due to their high dispersibility, small size effect, or the topological structure was formed between the wax layer and Teb@MBD nanoparticles. [45] The physicochemical relationship between the droplets and the micro/nano-structure of the leaf surface influences the retention of droplets on the leaf surface. [46] However, the cuticle layer on the leaf surface hinders the spread of liquid droplets because of its hydrophobicity.…”

Section: Foliar Adhesion Performancementioning

confidence: 99%

See 1 more Smart Citation

Bidirectional Uptake, Transfer, and Transport of Dextran‐Based Nanoparticles in Plants for Multidimensional Enhancement of Pesticide Utilization

Xiong,

Liang,

Shang

et al. 2023

Small

View full text Add to dashboard Cite

The development of effective multifunctional nano‐delivery approaches for pesticide absorption remains a challenge. Here, a dextran‐based pesticide delivery system (MBD) is constructed to deliver tebuconazole for multidimensionally enhancing its effective utilization on tomato plants. Spherical MBD nanoparticles are obtained through two‐step esterification of dextran, followed by tebuconazole loading using the Michael addition reaction. Confocal laser scanning microscopy shows that fluorescein isothiocyanate‐labeled MBD nanoparticles can be bidirectionally transported in tomato plants and a modified quick, easy, cheap, effective, rugged, and safe‐HPLC approach demonstrates the capacity to carry tebuconazole to plant tissues after 24 h of root uptake and foliar spray, respectively. Additionally, MBD nanoparticles could increase the retention of tebuconazole on tomato leaves by up to nearly 2.1 times compared with the tebuconazole technical material by measuring the tebuconazole content retained on the leaves. In vitro antifungal and pot experiments show that MBD nanoparticles improve the inhibitory effect of tebuconazole against botrytis cinerea by 58.4% and the protection against tomato gray molds by 74.9% compared with commercial suspensions. Furthermore, the MBD nanoparticles do not affect the healthy growth of tomato plants. These results underline the potential for the delivery system to provide a strategy for multidimensional enhancement of pesticide efficacy.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Foliar Adhesion Performancementioning

confidence: 99%

Bidirectional Uptake, Transfer, and Transport of Dextran‐Based Nanoparticles in Plants for Multidimensional Enhancement of Pesticide Utilization

Xiong,

Liang,

Shang

et al. 2023

Small

View full text Add to dashboard Cite

show abstract

Section: Triggering Apoptosis With Aie Therapeutic Agentsmentioning

confidence: 99%

“…In addressing this issue, the Tang group made significant progress by successfully conceiving a series of ER‐targeting AIEgens that initiated cancer cell apoptosis through ER stress (Figure 3I). [ 87 ] These compounds were all based on the keto‐salicylaldehyde parent and regulated the luminescence properties via the introduction of different electron‐withdrawing groups and the subcellular localization properties by varying the numbers and sites of phenolic hydroxyl groups. Among these probes, p‐CN‐DPAs displayed the highest fluorescence quantum yield and excellent ER targeting ability.…”

Section: Triggering Apoptosis With Aie Therapeutic Agentsmentioning

confidence: 99%

Activated aggregation‐induced emission therapeutics agents for triggering regulated cell death

Zhao,

Yu,

Zhang

et al. 2024

Aggregate

View full text Add to dashboard Cite

The induction of regulated cell death (RCD) through photo/ultrasound sensitization therapeutic agents has gained significant attention as a vital approach to combat drug resistance in tumors. Aggregation‐induced emission (AIE) therapeutic agents generate reactive oxygen species through photo/ultrasound activation, which can synergize with RCD inducers or directly induce RCD, ultimately resulting in the death of tumor cells. The presented comprehensive review delves into recent advancements in AIE therapeutic agents designed to trigger RCD or synergize with RCD inducers, encompassing apoptosis, necroptosis, pyroptosis, immunogenic cell death, autophagy, ferroptosis, and cuproptosis. Additionally, the intricate regulatory mechanisms through which activatory‐AIE therapeutics influence distinct RCD pathways are examined. A forward‐looking perspective on future developments and pertinent challenges within this exciting realm is presented, anticipating the continued evolution of activatable AIE therapeutics as a transformative approach to enhance tumor therapy.

show abstract

Pillar[5]arene and Azine Derivative Assembly Improved Dual‐Channel Detection of CN^–

Su,

Chen,

Sun

et al. 2024

Chin. J. Chem.

View full text Add to dashboard Cite

Comprehensive SummaryThe cyanide anion (CN–) is known to be one of the most toxic anions. Therefore, there is an urgent need to develop a reliable, sensitive, selective, rapid and effective method for the detection of CN–. Here, a self‐assembly strategy based on pillar[5]arene P5 and azine derivative AZ was used to construct supramolecular sensors, and it was found that the detection effect of CN– was significantly improved by the assembly strategy. The sensitivity of the assembled sensor P5‐AZ to CN– is more than 10 times higher than that of AZ. The detect mechanism was further investigated by theoretical calculations and 1H NMR. The results showed that AZ detects CN– by a deprotonation process with fluorescence enhancement, while P5‐AZ improves the sensitivity of CN– recognition through hydrogen bonding, anion‐π and anion‐dipole interactions, as well as the strong bonding ability of the assembly. Supramolecular assembly P5‐AZ has the advantages of low toxicity, high sensitivity, and more importantly, it provides a method to detect CN– sensitivity in the aqueous phase and organisms by host‐guest assembly.

show abstract

Referential modification strategy based on phenolic hydroxyl-containing KSA luminogens for ER-targeting probe construction

Cited by 6 publications

References 47 publications

Bidirectional Uptake, Transfer, and Transport of Dextran‐Based Nanoparticles in Plants for Multidimensional Enhancement of Pesticide Utilization

Bidirectional Uptake, Transfer, and Transport of Dextran‐Based Nanoparticles in Plants for Multidimensional Enhancement of Pesticide Utilization

Activated aggregation‐induced emission therapeutics agents for triggering regulated cell death

Pillar[5]arene and Azine Derivative Assembly Improved Dual‐Channel Detection of CN^–

Contact Info

Product

Resources

About

Referential modification strategy based on phenolic hydroxyl-containing KSA luminogens for ER-targeting probe construction

Cited by 6 publications

References 47 publications

Bidirectional Uptake, Transfer, and Transport of Dextran‐Based Nanoparticles in Plants for Multidimensional Enhancement of Pesticide Utilization

Bidirectional Uptake, Transfer, and Transport of Dextran‐Based Nanoparticles in Plants for Multidimensional Enhancement of Pesticide Utilization

Activated aggregation‐induced emission therapeutics agents for triggering regulated cell death

Pillar[5]arene and Azine Derivative Assembly Improved Dual‐Channel Detection of CN–

Contact Info

Product

Resources

About

Pillar[5]arene and Azine Derivative Assembly Improved Dual‐Channel Detection of CN^–