Reference Values of Selected Trace Elements in the Serum of Term Newborns from the Urban Area of Rome

Alimonti, Andrea; Petrucci, Francesco; Laurenti, F; Caroli, Sergio

doi:10.1007/0-306-47466-2_99

Cited by 2 publications

(3 citation statements)

References 9 publications

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“…The results show that, except for U (99.60%), the detection rates of other toxic elements were 100%. The concentration of the essential elements of the human body, such as Mg, Fe, Cu, and Zn, were similar to the reported values in the published literature [ 28 , 29 ], while the concentrations of Al, Sb, and Ba were clearly higher than those reported for healthy people [ 30 , 31 ], which is worth further study.…”

Section: Resultssupporting

confidence: 86%

A simple, rapid method for simultaneous determination of multiple elements in serum by using an ICP-MS equipped with collision cell

Zhang

Liu

et al. 2023

BMC Chemistry

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We developed an inductively coupled plasma mass spectrometry method for testing 23 elements, namely, Mg, Al, V, Cr, Mn, Fe, Co, Ni, Cu, Zn, As, Se, Rb, Sr, Mo, Cd, Sn, Sb, Ba, W, Tl, Pb, and U, in human serum. The serum samples were analyzed after diluting 1/25 with 0.5% nitric acid, 0.02% Triton-X-100, and 2% methanol. Sc, In, Y, Tb, and Bi were assigned internal standards to correct the baseline drift and matrix interference. The kinetic energy discrimination mode of the instrument with helium gas as the collision gas eliminated polyatomic interference. All 23 elements exhibited excellent linearity in their testing range, with a coefficient of determination ≥ 0.9996. The limits of detection of the 23 elements were within the range of 0.0004–0.2232 µg/L. The intra- and inter-day precision (relative standard deviation) were < 12.19%. The recoveries of the spiked standard for all elements were 88.98–109.86%. Among the 23 elements of the serum reference materials, the measured results of Mg, Al, Cr, Mn, Fe, Co, Ni, Cu, Zn, and Se were within the specified range of the certificate, and the results of the other elements were also satisfactory. The developed method was simple, rapid, and effective, and only 60 μL sample was consumed. A total of 1000 serum samples from healthy individuals were randomly selected from the Henan Rural Cohort, which reflects the status of serum elements in rural adults from the Northern Henan province of central China.

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Section: Resultssupporting

confidence: 86%

A simple, rapid method for simultaneous determination of multiple elements in serum by using an ICP-MS equipped with collision cell

Zhang

Liu

et al. 2023

BMC Chemistry

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“…The reviewed studies included healthy adult populations who served either as controls in case control studies or unexposed in cross-sectional and cohort studies. Blood chromium measured in these populations ranged from non-detectable levels to 0.92 µg/L, with median values from 0.15 µg/L to 0.42 µg/L [29,61,79], consistent with reference values reported to range from 0.01 to 1.2 µg/L [99,100]. It should be noted that a Chinese study involved a relatively large sample of 11,037 adults, representative of the general Chinese population [61].…”

Section: Discussionsupporting

confidence: 78%

“…However, serum Cr levels had median values of 1.66 µg/L [78] and 2.05 µg/L in [68], whereas the 75th percentiles reached 2.18 µg/L [78], 2.40 µg/L [89], and 4.98 µg/L [68]. Reference values for serum Cr have been reported to vary from 0.04 µg/L to 0.48 µg/L [99,100], much lower than those reported in the Chinese studies.…”

Section: Discussionmentioning

confidence: 98%

Human Health Effects of Oral Exposure to Chromium: A Systematic Review of the Epidemiological Evidence

Sazakli

2024

IJERPH

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The toxicity and carcinogenicity of hexavalent chromium via the inhalation route is well established. However, a scientific debate has arisen about the potential effects of oral exposure to chromium on human health. Epidemiological studies evaluating the connection between ingested chromium and adverse health effects on the general population are limited. In recent years, a wealth of biomonitoring studies has emerged evaluating the associations between chromium levels in body fluids and tissues and health outcomes. This systematic review brings together epidemiological and biomonitoring evidence published over the past decade on the health effects of the general population related to oral exposure to chromium. In total, 65 studies were reviewed. There appears to be an inverse association between prenatal chromium exposure and normal fetal development. In adults, parameters of oxidative stress and biochemical alterations increase in response to chromium exposure, while effects on normal renal function are conflicting. Risks of urothelial carcinomas cannot be overlooked. However, findings regarding internal chromium concentrations and abnormalities in various tissues and systems are, in most cases, controversial. Environmental monitoring together with large cohort studies and biomonitoring with multiple biomarkers could fill the scientific gap.

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Reference Values of Selected Trace Elements in the Serum of Term Newborns from the Urban Area of Rome

Cited by 2 publications

References 9 publications

A simple, rapid method for simultaneous determination of multiple elements in serum by using an ICP-MS equipped with collision cell

A simple, rapid method for simultaneous determination of multiple elements in serum by using an ICP-MS equipped with collision cell

Human Health Effects of Oral Exposure to Chromium: A Systematic Review of the Epidemiological Evidence

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