Reference Values of Body Composition Obtained by Dual Energy X-Ray Absorptiometry in Preterm and Term Neonates

Rigo, Jacques; Nyamugabo, K; Picaud, Jean‐Charles; Gérard, Paul; Pieltain, Catherine; Curtis, Mario De

doi:10.1097/00005176-199808000-00011

Cited by 164 publications

(127 citation statements)

References 21 publications

Supporting

Mentioning

111

Contrasting

Unclassified

Order By: Relevance

“…Females are shorter and weigh less than males at birth and throughout infancy but have more fat mass and less lean body mass than males, even in the neonatal period. [29][30][31] In 11-to 12-year olds the prevalence of overweight was higher in girls. 32,33 In Shantal children between 5 and 12 years old, fat patterning was different between girls and boys.…”

Section: Discussionmentioning

confidence: 98%

Tracking and determinants of subcutaneous fat mass in early childhood: the Generation R Study

Hokken-Koelega

Mook‐Kanamori

et al. 2008

Int J Obes

View full text Add to dashboard Cite

Objectives: To examine the development and tracking of subcutaneous fat mass in the first 2 years of life and to examine which parental, fetal and postnatal characteristics are associated with subcutaneous fat mass. Design: This study was embedded in the Generation R Study, a prospective cohort study from early fetal life onward. Subcutaneous fat mass was measured by skinfold thickness (biceps, triceps, suprailiacal, subscapular) at the ages of 1.5, 6 and 24 months in 1012 children. Information about parental, fetal and postnatal growth characteristics was collected by physical and fetal ultrasound examinations and questionnaires. Results: Normal values of subcutaneous fat mass are presented. Total subcutaneous fat mass was higher in girls than in boys at the age of 24 months (P ¼ 0.01). Subjects in the lowest and highest quartiles at the age of 6 months tended to keep their position in the same quartile at the age of 24 months (odds ratios 1.86 (95% confidence interval (CI) 1.3, 2.7)) and 1.84 (95% CI: 1.3, 2.6), respectively). Maternal height and weight, paternal weight, fetal weight at 30 weeks, birth weight and weight at the age of 6 weeks were each inversely associated with subcutaneous fat mass at the age of 24 months after adjustment for current weight at 24 months. Conclusion: This study shows for the first time that subcutaneous fat mass tends to track in the first 2 years of life. Furthermore, the results suggest that an adverse fetal environment and growth are associated with increased subcutaneous fat mass at the age of 24 months. Further studies are needed to examine whether these associations persist in later life.

show abstract

Section: Discussionmentioning

confidence: 98%

Tracking and determinants of subcutaneous fat mass in early childhood: the Generation R Study

Hokken-Koelega

Mook‐Kanamori

et al. 2008

Int J Obes

View full text Add to dashboard Cite

show abstract

“…31 The only instrument that has been validated in studies that prove its precision and accuracy is total body DEXA, especially the fan beam 4500 A model by HOLOGIC, used in this study, according to the recommendations of other validation studies. 23,[32][33][34][35] One pertinent subject, the question of when is the best moment to initiate motor physical therapy, still requires an answer. A recent study showed that initiating a physical therapy protocol between the first and second weeks of life did not produce any improvement in bone mineralization.…”

Section: Discussionmentioning

confidence: 99%

Effects of motor physical therapy on bone mineralization in premature infants: a randomized controlled study

2008

View full text Add to dashboard Cite

Objective: To study the effect of physical therapy on bone mineralization, weight gain and growth in preterm infants.Method: After fulfilling the inclusion criteria, preterm infants were matched for gestational age and birth weight and then randomly assigned to the physiotherapy group (PG, n ¼ 15) and control group (CG, n ¼ 14). The PG received motor physical therapy for 15 min daily, 5 times per week until hospital discharge. Bone mineralization was measured by total body dual energy X-ray beam absorptiometry (DEXA) at the onset and end of the study. Statistical analysis was realized by ANCOVA and linear correlation tests. Result:The physical therapy group (PG) presented greater body weight gain per day (27.4 ± 2.4 vs 21.01 ± 4.4 g, P<0.001) and length (1.3 ± 0.3 vs 0.8 ± 0.2 cm week À1 , P<0.001) than did the control group (CG). Body composition values verified by DEXA were greater for the PG. The mean gain in bone mineral content (BMC) (mg) was greater in the PG (434±247.5 vs À8.9±11.4, P<0.001), as was the mean bone mineral density (BMD) gain (mg cm À2 ) (8.4 ± 5.6 vs À3.1 ± 5.5, P<0.001). The gain in bone area (BA,cm 2 ) was 10.3±5 in the PG vs 1.5 ± 2 in the CG (P<0.001). The gain in lean mass (LM) (g) in the PG was also greater than in the CG (271.1±21.4 vs 109.1±1.0, P<0.009). The fat mass (g) was similar between the groups (P ¼ 0.432). Conclusion:These results showed that physiotherapy in preterm infants produced greater gains in growth, body weight, BMC, BMD, BA and LM.

show abstract

“…[1][2][3] Although the provision of bone-related nutrients at advised levels increases bone mineral accretion, ex utero bone mineral accretion rates do not equal in utero rates even with normal body weight gain. 4,5 Further, bone area (BA, cm 2 ) and mineral content (BMC, g) remain significantly lower than term infants at 1-year of age. 6,7 Older children and young adults who were born prematurely have significantly shorter stature with lower bone size and mineral content than their peers.…”

Section: Introductionmentioning

confidence: 92%

Maternal-administered physical activity enhances bone mineral acquisition in premature very low birth weight infants

et al. 2008

View full text Add to dashboard Cite

Objective: To determine if physical activity delivered by an infant's mother would be as effective in promoting bone mineral acquisition in preterm very low birth weight (VLBW) infants as the same intervention administered by a trained therapist.Patients and methods: Preterm VLBW infants were randomized to receive daily physical activity administered by the infant's mother (MOM, n ¼ 11) or a trained therapist (OT, n ¼ 11), or control (n ¼ 11). Physical activity consisted of range of motion movements against passive resistance to all extremities for 5 to 10 min daily. All infants were fed mother's milk with fortification to 24 kcal oz À1 . Dual energy x-ray of the forearm bone area (BA, cm 2 ), mineral content (BMC, g), and density (BMD, g/cm 2 ) and measurement of bone formation (bone-specific alkaline phosphatase, BAP) and resorption (urine pyridinium crosslinks of collagen, Pyd) were obtained at study entry and at 2.0 kg of body weight.Result: Forearm BA and BMC gains were greater in MOM and OT infants compared to the control infants despite similar postnatal growth rate and nutrient intake. Serum BAP levels decreased in controls but remained unchanged in MOM and OT infants. Urine Pyd levels were similar at baseline to 2.0 kg for all groups. These findings suggest greater bone growth and mineral acquisition in MOM and OT infants than control infants. Conclusion:This study demonstrates that a physical activity program administered by the infant's own mother is as equally effective as therapist-administered physical activity in promoting greater bone growth and mineral acquisition in preterm VLBW infants.

show abstract

Reference Values of Body Composition Obtained by Dual Energy X-Ray Absorptiometry in Preterm and Term Neonates

Abstract: Normative data of dual-energy x-ray absorptiometry body composition for healthy preterm and term infants are provided and can therefore be used in research and in clinical practice.

Cited by 164 publications

References 21 publications

Tracking and determinants of subcutaneous fat mass in early childhood: the Generation R Study

Tracking and determinants of subcutaneous fat mass in early childhood: the Generation R Study

Effects of motor physical therapy on bone mineralization in premature infants: a randomized controlled study

Maternal-administered physical activity enhances bone mineral acquisition in premature very low birth weight infants

Contact Info

Product

Resources

About