Reference Values for Performance on the Automated Neuropsychological Assessment Metrics V3.0 in an Active Duty Military Sample

Reeves, Dennis; Bleiberg, Joseph; Roebuck-Spencer, Tresa; Cernich, Alison N.; Schwab, Karen; Ivins, Brian; Salazar, Andrés M.; Harvey, Sally; Brown, F. H. S.; Warden, Deborah L.

doi:10.7205/milmed.171.10.982

Cited by 54 publications

(27 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The ANAM subtests have been described in detail in a previous publication (Reeves et al, 2006). See Table 2 for list of subtests, abbreviations, and cognitive domains are assessed by ANAM.…”

Section: Methodsmentioning

confidence: 99%

Associations between interhemispheric functional connectivity and the Automated Neuropsychological Assessment Metrics (ANAM) in civilian mild TBI

Sours

Rosenberg

Kane

et al. 2014

Brain Imaging and Behavior

View full text Add to dashboard Cite

This study investigates cognitive deficits and alterations in resting state functional connectivity in civilian mild traumatic brain injury (mTBI) participants with high and low symptoms. Forty-one mTBI participants completed a resting state fMRI scan and the Automated Neuropsychological Assessment Metrics (ANAM) during initial testing (<10 days of injury) and a one month follow up. Data were compared to 30 healthy control subjects. Results from the ANAM demonstrate that mTBI participants performed significantly worse than controls on the code substitution delayed subtest (p=0.032) and weighted throughput score (p=0.001). Among the mTBI patients, high symptom mTBI participants performed worse than those with low symptoms on the code substitution delayed (p=0.017), code substitution (p=0.012), repeated simple reaction time (p=0.031), and weighted throughput score (p=0.009). Imaging results reveal that during the initial visit, low symptom mTBI participants had reduced interhemispheric functional connectivity (IH-FC) within the lateral parietal lobe (p=0.020); however, during follow up, high symptom mTBI participants showed reduced IH-FC compared to the control group within the dorsolateral prefrontal cortex (DLPFC) (p=0.013). Reduced IH-FC within the DLPFC during the follow-up was associated with reduced cognitive performance. Together, these findings suggest that reduced rs-FC may contribute to the subtle cognitive deficits noted in high symptom mTBI participants compared to control subjects and low symptom mTBI participants.

show abstract

Section: Methodsmentioning

confidence: 99%

Associations between interhemispheric functional connectivity and the Automated Neuropsychological Assessment Metrics (ANAM) in civilian mild TBI

Sours

Rosenberg

Kane

et al. 2014

Brain Imaging and Behavior

View full text Add to dashboard Cite

show abstract

“…Further, many of the subjects were paratroopers, which have been shown in previous studies (Ivins et al, 2003) to have slightly higher rates of head injuries than nonparatroopers, both prior to and after entering the Army. Interestingly, however, an analysis presented elsewhere (Reeves et al, 2006) revealed that previously reported head injury had little to no impact on ANAM performance, with the exception that the most severe injuries (LOC > 60 minutes) resulted in slower reaction times on the SRT subtest.…”

Section: Figure 3amentioning

confidence: 85%

Influence of Demographics on Computerized Cognitive Testing in a Military Sample

Roebuck-Spencer

Reeves

Bleiberg

et al. 2008

Military Psychology

View full text Add to dashboard Cite

Computerized cognitive testing with software programs such as the Automated Neuropsychological Assessment Metrics (ANAM) have long been used to assess cognition in military samples. This study describes demographic influences on computerized testing performance in a large active duty military sample (n = 2366). Performance differences between men and women were minimal on most ANAM subtests, but there was a clear speed/accuracy trade-off, with men favoring speed and women favoring accuracy on the Continuous Performance Test (CPT) subtest. As expected, reaction time increased with age on most subtests, with the exception of Mathematical Processing Test (MTH). Higher education resulted in significant but minimal performance increases on Code Substitution (CDS), Matching to Sample (MSP), and Memory Search (STN) subtests. In contrast, substantial performance differences were seen between education groups on the MTH subtest. These data reveal that it is important to consider demographic factors, particularly age, when using ANAM to draw conclusions about military samples. These results also point to the importance of exploring demographic influences for all reaction time-based computerized assessment batteries.

show abstract

“…The SRT was taken from the Automated Neuropsychological Assessment Metrics (ANAM; Reeves et al, 2006) and was used to measure inattention. Participants executed a key press as quickly as possible to a target presented on the computer screen at variable intervals.…”

Section: Methodsmentioning

confidence: 99%

Inattention, impulsive action, and subjective response to d-amphetamine

Weafer¹,

Wit²

2013

Drug and Alcohol Dependence

View full text Add to dashboard Cite

Background Both impulsivity and sensitivity to the rewarding effects of drugs have long been considered risk factors for drug abuse. There is some preclinical evidence to suggest that the two are related; however, there is little information about how specific behavioral components of impulsivity are related to the acute euphorigenic effects of drugs in humans. The aim of the current study was to examine the degree to which both inattention and impulsive action predicted subjective response to amphetamine. Methods Healthy adults (n=165) performed the behavioral tasks and rated their subjective response to amphetamine (0, 5, 10, and 20 mg). Inattention was assessed as attention lapses on a simple reaction time task, and impulsive action was measured by stop RT on the stop task. Subjective response to amphetamine was assessed with the Drug Effects Questionnaire (DEQ) and the Profile of Mood States (POMS). Results Hierarchical linear regression analyses showed significant negative associations between attention lapses and subjective response to amphetamine on DEQ measures. By contrast, stop RT was positively associated with responses on both DEQ and POMS measures. Additionally, a dose-response relationship was observed, such that the strength of these associations increased with higher doses of amphetamine. Conclusions These findings suggest that inattention is associated with less subjective response to amphetamine. By contrast, the heightened sensitivity to stimulant drug reward observed in individuals high in impulsive action suggests that this might be one mechanism contributing to increased risk for stimulant drug abuse in these individuals.

show abstract

Reference Values for Performance on the Automated Neuropsychological Assessment Metrics V3.0 in an Active Duty Military Sample

Cited by 54 publications

References 10 publications

Associations between interhemispheric functional connectivity and the Automated Neuropsychological Assessment Metrics (ANAM) in civilian mild TBI

Associations between interhemispheric functional connectivity and the Automated Neuropsychological Assessment Metrics (ANAM) in civilian mild TBI

Influence of Demographics on Computerized Cognitive Testing in a Military Sample

Inattention, impulsive action, and subjective response to d-amphetamine

Contact Info

Product

Resources

About