Reference values for local arterial stiffness. Part A

Engelen, L.; Bossuyt, Jelle; Ferreira, Isabel; Bortel, Luc M. Van; Reesink, Koen D.; Segers, Patrick; Stehouwer, Coen D. A.; Laurent, Stéphane; Boutouyrie, Pierre

doi:10.1097/hjh.0000000000000654

Cited by 101 publications

(94 citation statements)

References 46 publications

(63 reference statements)

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“…The practical relevance of our findings becomes evident when considering the reference values for carotid artery distensibility [3]. Engelen et al showed that the difference in carotid distension between the healthy subpopulation and the subpopulation with prior cardiovascular disease is about 0.10 mm.…”

Section: Discussionmentioning

confidence: 57%

“…In this subgroup, distension in study participants with at least one cardiovascular risk factor (i.e. smoking and self-reported diabetes) was found to be 0.05 mm smaller than in study participants without risk factors [3].…”

Section: Discussionmentioning

confidence: 59%

“…Recently, reference values for local carotid artery stiffness have been established [3], supporting its clinical application as a diagnostic marker for vascular dysfunction.…”

Section: Introductionmentioning

confidence: 97%

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Head orientation should be considered in ultrasound studies on carotid artery distensibility

Holtackers

Spronck

Heusinkveld

et al. 2016

Journal of Hypertension

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Section: Discussionmentioning

confidence: 57%

Section: Discussionmentioning

confidence: 59%

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Head orientation should be considered in ultrasound studies on carotid artery distensibility

Holtackers

Spronck

Heusinkveld

et al. 2016

Journal of Hypertension

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“…These patients showed a 13% improvement in both PWV and carotid stiffness, 6% increase in ICD, 7% increase in IMT, and a 17% reduction in CWS. These changes are important since they correspond grossly to 10/15 years of normal vascular aging 23, 24, 25. This improvement persisted unchanged after adjustment for dialysis duration and other potential confounders.…”

Section: Discussionmentioning

confidence: 82%

Reversal of Arterial Stiffness and Maladaptative Arterial Remodeling After Kidney Transplantation

Karras

Boutouyrie

Briet

et al. 2017

JAHA

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BackgroundChronic kidney disease is characterized by stiffening, thinning, dilatation, and increased circumferential wall stress of large arteries, associated with increased cardiovascular risk. Kidney transplantation (KT) reverses many pathological features of chronic kidney disease and improves life expectancy; however, longitudinal studies exploring the impact of KT on recipient large arteries are scarce.Methods and ResultsThis study was designed to appraise arterial changes following KT. Carotid‐femoral pulse wave velocity, carotid remodeling (circumferential wall stress and carotid internal diameter), and stiffness were measured in 161 consecutive recipients receiving either a living (n=49) or a deceased (n=112) donor allograft, at 3 and 12 months after transplantation. Mean pulse wave velocity decreased from 10.8 m/s (95% confidence interval, 10.5–11.2 m/s) (at month 3) to 10.1 m/s (95% confidence interval, 9.8–10.5 m/s) (at month 12) (P<0.001). After multivariate adjustment, pulse wave velocity reduction from month 3 to month 12 was significantly larger in the living donor allograft KT (P<0.001). Circumferential wall stress decreased, 70 kPa (95% confidence interval, 68–72 kPa) to 64 kPa (95% confidence interval, 62–67 kPa), as well as carotid internal diameter and carotid stiffness (P<0.001 for all). Reductions in circumferential wall stress, diameter, and stiffness were significantly larger in the living donor allograft KT (P<0.001). When deceased donor allograft patients were classified into standard and expanded criteria donors, changes in both pulse wave velocity and circumferential wall stress were blunted in expanded criteria donors. Changes were independent of graft function and blood pressure changes.ConclusionsLarge‐artery stiffness and maladaptive carotid artery remodeling of chronic kidney disease is partially reversed within 12 months of KT and appears unrelated to renal function. Improvements were independently associated with live organ donation. Our data suggest that expanded criteria donors may hamper vascular recovery.

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“…Three measurements were made and the mean value was calculated. For local carotid and femoral distensibility, normal and reference values were recently published but reference values for aortic stiffness were not available (30,31). Generally, these parameters used in clinical studies were compared with those in the controls.…”

Section: Measurement Of Aortic Stiffness Parameters With Echocardiogrmentioning

confidence: 99%

Effects of Varenicline on Cardiovascular Parameters and Oxidative Stress

Sarıoğlu¹,

Erken²,

Ayhan³

et al. 2017

Eurasian J Pulmonol

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Reference values for local arterial stiffness. Part A

Cited by 101 publications

References 46 publications

Head orientation should be considered in ultrasound studies on carotid artery distensibility

Head orientation should be considered in ultrasound studies on carotid artery distensibility

Reversal of Arterial Stiffness and Maladaptative Arterial Remodeling After Kidney Transplantation

Effects of Varenicline on Cardiovascular Parameters and Oxidative Stress

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