Reference range of thyroid function (FT3, FT4 and TSH) among Indian adults

Marwaha, Raman K.; Tandon, Nikhil; Ganie, Mohd Ashraf; Mehan, Neena; Sastry, A. V. R.; Garg, MK; Bhadra, Kuntal; Singh, Simar Rajan

doi:10.1016/j.clinbiochem.2012.09.021

Cited by 24 publications

(18 citation statements)

References 29 publications

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“…We speculated with caution that apparently thyroid healthy individuals were likely to be recruited without rigorous exclusion criteria and iodine nutritional status was also not considered when the manufactures established the RIs of thyroid hormones. Table 4 shows the RIs of thyroid hormones reported by the investigators in various countries and regions during the past decade [11][12][13][16][17][18][19][20][21][22]. Our upper-limit of serum TSH level was marginally higher than Guan's results but similar with Li's results [11,13].…”

Section: Discussioncontrasting

confidence: 41%

“…Our results showed that significant differences among all the age groups were observed in FT 3 , but neither in TSH nor in FT 4 . The findings were in accord with substantial previous studies [12,21,22,24,25], but were inconsistent with several other studies [13,17,20]. The possible explanations might be associated with the differences of race and iodine nutritional status [17,24,26,27].…”

Section: The Effects Of Age and Gender On Tsh And Other Thyroid Hormosupporting

confidence: 40%

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Reference intervals of thyroid hormones in a previously iodine-deficient but presently more than adequate area of Western China: a population-based survey

et al. 2016

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Section: Discussioncontrasting

confidence: 41%

Section: The Effects Of Age and Gender On Tsh And Other Thyroid Hormosupporting

confidence: 40%

Reference intervals of thyroid hormones in a previously iodine-deficient but presently more than adequate area of Western China: a population-based survey

et al. 2016

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“…A study done in more than 4000 Delhi adults shows that mean TSH value was 2.2 ± 0.9 mIU/L. 17 In another study done in India shows that TSH with increasing BMI. As the BMI increased, mean TSH in the BMI range also increased.…”

Section: Subclinical Hypothyroidism and Leg Swellingmentioning

confidence: 95%

Subclinical hypothyroidism as a cause of leg swelling in patients attending tertiary level hospital in Kathmandu

Adhikari¹,

Pathak²

2018

J Pathol Nep

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Background: Peripheral edema is one of the common causes of visit to medical outpatient department. After history taking and investigations few patients are left without diagnosis. This study was designed to find if there is any association between pedal edema and subclinical hypothyroidism when there is no other systemic disease is found.Materials and Methods: This is a cross-sectional observational hospital based study done in one of Medical colleges in Kathmandu for a period of 2 years .All patient coming to medical OPD for the first time with bilateral painless limb swelling were evaluated data were tabulated and analyzed using Ms Excel.Results: Out of 300 patients, 146 patients were exclude from history and clinical evaluation, 154 patients underwent laboratory evaluation. After investigations 46 patients were left without any other systemic disease. Out of them only 3 were male. About 40% of them are overweight or obese. 57% of them had high TSH level, which was significantly associated with limb swelling (t=0.012)Conclusion: Subclinical hypothyroidism is significantly associated with painless bilateral limb swelling when there is no other systemic cause. It is logical to investigate a limb swelling with thyroid function test however there needs to be a larger interventional study to exactly point out the cause in these patients.

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“…The mean age of non pregnant women was 2515 years and their body mass index was 263. 4 In another study done on normal pregnant Indian women by Marwah et al 13 FT3, FT4, & TSH values in pregnant women were evaluated trimester wise. The mean values of TSH for each trimester was 2.421.65,2.491.9,2.61.9 respectively.…”

Section: Fig 5: Mean Value Of Serum Total T4mentioning

confidence: 99%

Establishment of reference intervals of thyroid function test in healthy individuals

2020

IJCBR

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Aim: The central role of the laboratory is to aid the clinician, in interpreting observed values, by providing relevant reference values. To prevent ambiguities inherent in the term normal values, a laboratory should establish its own reference limits. Therefore, the current study was aimed at establishing the reference range of Thyroid function test in healthy population. Study design: This was a retrospective cross sectional study on 1000 healthy individuals above 18 years of age, attending the routine health checkup. Materials and Methods: Partitioning was done according to age and sex, inclusion and exclusion criteria were applied and T3, T4 and TSH levels were estimated on the study group. Results: The values of T3 and T4 obtained were (mean and reference interval in nmol/L) 1.85 (1.15-2.55) and 100.58(57.35-143.81)respectively for males and 1.87(1.07-2.55) and 110.49(62.46-158.52) respectively for females. Similarly, TSH values were 1.23 (0.37-5.19) mIU/L and 1.37(0.27-5.63) mIU/L in males and females respectively. Conclusion: We found that the value of serum Total T3 & serum Total T4 was higher as compared to the international values while that serum TSH was similar.

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Reference range of thyroid function (FT3, FT4 and TSH) among Indian adults

Cited by 24 publications

References 29 publications

Reference intervals of thyroid hormones in a previously iodine-deficient but presently more than adequate area of Western China: a population-based survey

Reference intervals of thyroid hormones in a previously iodine-deficient but presently more than adequate area of Western China: a population-based survey

Subclinical hypothyroidism as a cause of leg swelling in patients attending tertiary level hospital in Kathmandu

Establishment of reference intervals of thyroid function test in healthy individuals

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