Reference intervals of amino acid for newborns in North Asia: Diagnosing Inborn Errors of Metabolism Using Liquid Chromatography Tandem Mass Spectrometry
Abstract:Aim. To establish reference intervals for blood amino acids in healthy newborns of North Asia measured by liquid chromatography tandem mass spectrometry and evaluate their differences from respective reference values for newborns from other populations.
Objectives. A cross-sectional study of 381 healthy newborns was conducted. De-identified dried blood spots annotated by age, birth-weight, and sex were obtained from 381 healthy newborns aged 0-7 days. Data was collected from April to May of 2020.
Methods. Dr… Show more
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