Reference Charts of Fetal Biometric Parameters in 31,476 Brazilian Singleton Pregnancies

Abstract

Fetal biometric parameters were determined for a large Brazilian population, and they may serve as reference values in cases with a high risk of intrauterine growth disorders.

"Parametry biometryczne płodu: wykresy odniesienia dla nieselektywnej populacji ryzyka z Uberaby w Brazylii"

“…In our study, all ultrasound exams were performed by only two experienced examiners with FMF accreditation, and the ultrasound exams were performed using only two apparatuses. Comparing our results with those of Araujo Júnior et al (16) between 18 and 38 weeks of gestation, the means of BPD, AC, FDL and EFW were similar, showing that the ethical factor did not have a significant importance in this local sample of Brazilian population. However, new studies with larger samples including other Brazilian regions are necessary to prove the real influence of ethical effect on the fetal biometry.…”

“…As we did not observe significant differences between the fetal biometric parameter measurement obtained in our study and the ones from Araujo Júnior et al (16) , who assessed a larger Brazilian population sample, we believe that our sample can represent a great miscegenation of the Brazilian population. These reference charts may be used in Brazilian pregnant women with high-risk of intrauterine growth disorders.…”

“…Araujo Júnior et al (16) determined reference charts for fetal biometric parameters in 31,476 singleton Brazilian pregnant women. This study was carried out in the metropolitan region of Sao Paulo city, which also presents different rates of mixed population regarding the whole Brazilian population.…”

“…All these reference charts were unconditional (cross-sectional) studies, because they are more appropriate for the quantification of fetal size (15) . There is a unique unconditional study with 31,476 singleton Brazilian pregnant women which established reference charts for fetal biometric parameters (16) . However, because of a lot of miscegenation of Brazilian population with great ethnic differences among its regions, it is not possible to establish reference charts for fetal biometric parameters to the whole Brazilian population.…”

First-trimester intrauterine Zika virus infection and brain pathology: prenatal and postnatal neuroimaging findings

“…Moreover, her first‐trimester screening test for common trisomies was normal at 13 weeks, and the second‐trimester scan showed normal fetal anatomy at 19 weeks. However, growth ultrasonography performed at 29 weeks showed fetal growth restriction (FGR) according to local reference ranges: the estimated fetal weight was at the first percentile for the GA, and the head circumference (HC) was 22.1 cm, which was below 1 standard deviation (SD) of the expected value for the GA. In view of these findings, the mother was referred for detailed ultrasonography assessment by a fetal medicine specialist.…”