2011
DOI: 10.1016/j.clnu.2010.12.001
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Refeeding hypophosphataemia is more common in enteral than parenteral feeding in adult in patients

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Cited by 86 publications
(74 citation statements)
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“…RH was commonly observed in patients receiving PN due to high levels of glucose in PN solutions, which stimulates insulin secretion, and this hyperinsulinemic state leads to hypophosphatemia, hypopotassemia, and hypomagnesemia (18). However, recent studies showed that RH was more prevalent in patients receiving EN compared to those receiving PN solutions (6,17,28). This could be explained by 3 different mechanisms.…”
Section: Discussionmentioning
confidence: 61%
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“…RH was commonly observed in patients receiving PN due to high levels of glucose in PN solutions, which stimulates insulin secretion, and this hyperinsulinemic state leads to hypophosphatemia, hypopotassemia, and hypomagnesemia (18). However, recent studies showed that RH was more prevalent in patients receiving EN compared to those receiving PN solutions (6,17,28). This could be explained by 3 different mechanisms.…”
Section: Discussionmentioning
confidence: 61%
“…Hoffmann et al (4) showed a 30% mortality rate in hospitalized patients with severe hypophosphatemia. There was no increased mortality rate in the first 7 days of ICU stay in a study performed by Zeki et al (17), and, similarly, Lubart et al (30) did not find an increased mortality rate for 7 days and 1 month in 40 elderly patients with RH. In a study performed in 55 septic patients, severe hypophosphatemia increased mortality rates by 8-fold (2).…”
Section: Discussionmentioning
confidence: 83%
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“…En un estudio realizado en pacientes con cáncer a los que se les iniciaba SNE, se encontró una incidencia de hipofosfatemia de realimentación del 24,5%, 37,5% entre los pacientes con NE y 18,5% en el subgrupo con NP (14), diferencia confirmada posteriormente en otros trabajos (15). Esto puede estar en relación con el hecho de que la NE estimula una mayor secreción de insulina que la NP a través del efecto incretina, lo que amplifica el mecanismo que conduce al síndrome de realimentación.…”
Section: Discussionunclassified
“…De ellos, el 28,7% presentó algún grado de hipofosfatemia, frente al 33% del subgrupo que recibía NE en el trabajo de Zeki y cols. (consideraban exclusivamente cifras de fosfato inferiores a 1,8 mg/dl) (15). Contrariamente a lo observado en los estudios mencionados, no se pudo demostrar una relación estadísticamente significativa entre la aparición de hipofosfatemia y la presencia de riesgo de síndrome de realimentación según las guías NICE.…”
Section: Discussionunclassified