Reductive Cyclization of δ‐Hydroxy Nitriles: A New Synthesis of Glycosylamines.

Manganese catalyzed cross-coupling of allylic alcohols and nitriles: an elegant route for access to δ-hydroxynitriles

“…1,2 Especially, δ-hydroxynitriles are frequently used as versatile building blocks for the synthesis of diols, lactones, lactams, amino alcohols and cyclic amine derivatives. [3][4][5][6][7] Typically, δ-hydroxynitriles are often encountered in various biologically active molecules, pharmaceuticals, and natural products, as shown in Fig. 1.…”