Reduction, proliferation, and differentiation defects of stem cells over time: a consequence of selective accumulation of old centrioles in the stem cells?

Editorial: Molecular mechanism of ageing and therapeutic advances through targeting glycative and oxidative stress

“…The inexorable passage of time has always intrigued humanity, prompting an incessant quest for unravelling the mysteries underlying the ageing process. However one should distinguish between the ageing of the organism and cellular senescence ( Tkemaladze, 2023 ). During the process of cellular ageing (senescence), cells lose the ability to divide and become senescent either due to reaching the Hayflick limit ( Hayflick, 1965 ) or due to stress factors.…”