Reduction pneumonoplasty for patients with a forced expiratory volume in 1 second of 500 milliliters or less

Eugene, John; Dajee, Amrit; Kayaleh, Raouf A.; Gogia, Harmohinder S; C, Dos Santos; Gazzaniga, A.

doi:10.1097/00128594-199707000-00025

Cited by 6 publications

(7 citation statements)

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“…Some series suggest that a very low FEV 1 is associated with an increased risk of death postoperatively, 30 whereas others do not. 10,31,32 Some case series suggest that a very low carbon monoxide diffusing capacity increases the risk, 33,34 whereas others have not confirmed this finding. 32,[35][36][37][38] A recent trial of lung-volume-reduction surgery involving 48 patients stopped enrolling participants who had a carbon monoxide diffusing capacity that was less than 30 percent of their predicted value or who were unable to walk 150 m (492 ft) on the shuttle-walking test, because 5 of the first 15 patients died (3 in the surgical group and 2 in the medical group).…”

Section: Discussionmentioning

confidence: 99%

Patients at High Risk of Death after Lung-Volume–Reduction Surgery

et al. 2001

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Section: Discussionmentioning

confidence: 99%

Patients at High Risk of Death after Lung-Volume–Reduction Surgery

et al. 2001

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“…The Borg scale was used in two studies 48. In the series reported by Eugene et al 29 the mean score decreased from 7.6 before surgery to 4.65 postoperatively, and Zenati et al 38 reported a decrease from 3.71 to 2.4. (The extreme difference in baseline is accounted for by the fact that the patients in the study of Eugene et al 29 were all very ill.) The Mahler baseline dyspnoea index (BDI) and transitional dyspnoea index (TDI) were used by a number of studies 49.…”

Section: Resultsmentioning

confidence: 91%

“…In the series reported by Eugene et al 29 the mean score decreased from 7.6 before surgery to 4.65 postoperatively, and Zenati et al 38 reported a decrease from 3.71 to 2.4. (The extreme difference in baseline is accounted for by the fact that the patients in the study of Eugene et al 29 were all very ill.) The Mahler baseline dyspnoea index (BDI) and transitional dyspnoea index (TDI) were used by a number of studies 49. Three studies reported scores for the functional impairment component individually31 38 39 with BDI scores of 0.83, 0.9, and 1.0, respectively, and TDI scores of 2.2, 1.65, and 1.72.…”

Section: Resultsmentioning

confidence: 91%

Lung volume reduction surgery (LVRS) for chronic obstructive pulmonary disease (COPD) with underlying severe emphysema

Young

Fry‐Smith

Hyde

1999

Thorax

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Background-Lung volume reduction surgery (LVRS) has recently re-emerged as a surgical option for the treatment of end stage chronic obstructive pulmonary disease (COPD) due to underlying severe emphysema. Advocates of LVRS claim that it represents a significant breakthrough in the management of this challenging group of patients while sceptics point to uncertainty about the eVectiveness of the operation. Methods-A systematic review was conducted of the evidence on the eVects of LVRS in patients with end stage COPD secondary to severe emphysema. Results-The most rigorous evidence on the eVectiveness of LVRS came from case series. Seventy five potentially relevant studies were identified and 19 individual series met the methodological criteria for inclusion. The pattern of results was consistent across individual studies despite a significant degree of clinical heterogeneity. Significant short term benefits occurred across a range of outcomes which appeared to continue into the longer term. Physiological improvements were matched by functional and subjective improvements. Early mortality rates were low and late mortality rates compared favourably with those of the general COPD population. However, the entire research base for the intervention is subject to the limitations of study designs without parallel control groups.Conclusions-LVRS appears to represent a promising option in the management of patients with severe end stage emphysema. However, until the results of ongoing clinical trials are available, the considerable uncertainty that exists around the eVectiveness and cost eVectiveness of the procedure will remain.

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“…15 This is an interaction between personality and psychological state, on the one hand, and the level of symptoms for suggests that with increasing experience the risk falls even among the most severely affected patients. 15 This is an interaction between personality and psychological state, on the one hand, and the level of symptoms for suggests that with increasing experience the risk falls even among the most severely affected patients.…”

Section: Lvrs: Who and When?mentioning

confidence: 99%