Reduction of the infarcted area with the use of simplified coronary sinus retroperfusion during experimental coronary artery occlusion

Katırcıoğlu, Salih Fehmi; Gökçe, Perran; Ulus, A. Tulga; Tütün, Ufuk; Apaydin, Nusret; Koç, Bahattin Taylan

doi:10.1016/s0167-5273(99)00213-2

Cited by 8 publications

(6 citation statements)

References 24 publications

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“…Hence, ARP may be a valuable short-term method (bridge) for maintaining ischemic myocardium viability in patients awaiting coronary angioplasty or revascularization. Although this has been shown to be promising in animals (21,30,46), clearly further validation will be necessary.…”

Section: Potential Clinical Utilitymentioning

confidence: 99%

Coronary venous retroperfusion: an old concept, a new approach

Kassab

Navia

March³

et al. 2008

Journal of Applied Physiology

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The potential of the coronary veins for revascularization has been evaluated by many investigators for more than a century. The major hurdle has been the damage of veins during sudden exposure to arterial pressure. The solution to this problem has typically involved the use of intricate and complicated apparatus and devices, which has prevented routine clinical utility in the catheterization laboratory. This review examines this old concept from a new perspective and proposes a novel hypothesis to address previous shortcomings. We speculate on an approach that may serve to eliminate the edema and hemorrhage that result during venous retroperfusion as the pressure is suddenly increased to arterial values. We propose the rationale to increase the venous pressure to arterial values more gradually to allow prearterializations of the veins before full exposure of arterial pressure. Finally, we discuss various possible indications for this selective autoretroperfusion strategy to combat myocardial ischemia in cardiogenic shock patients, ST-elevation myocardial infarct patients, no-option patients, and beyond.

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Section: Potential Clinical Utilitymentioning

confidence: 99%

Coronary venous retroperfusion: an old concept, a new approach

Kassab

Navia

March³

et al. 2008

Journal of Applied Physiology

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“…Experimental and clinical results have shown that myocardial blood supply can be preserved with retrograde CS perfusion 13‐15 . Our results also showed that myocardial blood supply can be achieved with simplified CS retroperfusion 10 . Regarding the results of 14 patients in this series, the protection seems to be effective.…”

Section: Discussionmentioning

confidence: 52%

“…Based on our off‐pump experience and previous experimental studies, we intended to transfer our knowledge to heart valve surgery 10‐12 . In order to perform aortic valve replacement with CPB while the heart was beating, we selected CS as the site for oxygenated blood delivery.…”

Section: Discussionmentioning

confidence: 99%

Aortic Valve Replacement With On-Pump Beating Heart Technique

et al. 2007

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“…Due to improvements in myocardial preservation techniques, operative mortality risk and postoperative morbidity rates were decreased (6). Retrograde perfusion of the heart through coronary sinus cannula and achievement of myocardial preservation was already presented in the literature (7,8,9).…”

Section: Discussionmentioning

confidence: 99%

Does beating heart surgery technique reduce the mortality and morbidity after redo valve operations?

Mungan

Demi̇rdaş

nay

et al. 2018

Sanamed

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Aim: The aim of this study was to determine the effect of beating heart technique on mortality and morbidity after redo valve operations.Material and Method: Fifty-two patients who had redo open-heart surgery between May 2005 and November 2006 in a Hospital included in this prospective study. All patients had a history of open-heart surgery with median sternotomy. Thirty-two patients who had redo open-heart surgery with beating heart technique were included in Group 1 and 20 patients who had redo open-heart surgery with conventional cardioplegic myocardial arrest technique were included in Group 2. Patients who had any cardiac surgery without median sternotomy were excluded. Results: Functional capacity according to New York Heart Association classification was significantly lower and number of patients with chronic obstructive lung disease was significantly higher in Group 1 (p = 0.011 and p = 0.003 respectively). There was no significant difference in other preoperative variables. Operation, cardiopulmonary bypass and aortic cross-clamping times were significantly higher in Group 2 (p = 0.001, p = 0.003, p = 0.04 respectively). Mechanical ventilation, inotropic agent support and hospitalization times were significantly higher in Group 2 (p < 0.05). Intensive care unit time was significantly longer in Group 1 (p < 0.05). Drainage volumes, blood product transfusion volumes, intra-aortic balloon pump support times were not significantly different between the groups.Conclusion: Beating heart technique in redo heart valve operations has better outcomes than the conventional technique.

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Reduction of the infarcted area with the use of simplified coronary sinus retroperfusion during experimental coronary artery occlusion

Cited by 8 publications

References 24 publications

Coronary venous retroperfusion: an old concept, a new approach

Coronary venous retroperfusion: an old concept, a new approach

Aortic Valve Replacement With On-Pump Beating Heart Technique

Does beating heart surgery technique reduce the mortality and morbidity after redo valve operations?

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