Reduction of Some Conjugated Azomethine Systems by Aryl Thiols

Some Derivatives of Tetrahydrothiapyran as Possible Local Anesthetics

“…This amine is a weak base (Kh 1.86 X 10~ ) and undergoes the usual amine reactions. 4-Aminotetrahydrothiapyran-l-dioxide (III), the sulfone of II, was prepared by the reduction of the oxime of tetrahydro-l,4-thiapyran-l-dioxide with hydrogen and Raney nickel in good yields. It was made also by the oxidation of an amide of II followed by hydrolysis.…”