Reduction of salivary tumor necrosis factor alpha levels in response to magic mouthwash with Curcuma xanthorriza in cancer patients undergoing chemotherapy

Sufiawati, Irna; Gunawan, Indra; Wijaya, Indra; Rusdiana, Taofik; Subarnas, Anas

doi:10.12991/jrp.2018.108

Cited by 3 publications

(2 citation statements)

References 19 publications

(21 reference statements)

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“…amada), show strong cytotoxicity in a leukaemic cell line and in peripheral blood mononuclear cells, as well as having antioxidant and haemolysis properties [41]. Dry extracts from rhizomes of C. xanthorrhiza and C. zedoaria have been shown to have anticancer and antiviral properties [42][43][44]. Furthermore, volatile oils extracted from leaves of C. caesia have broad antioxidant, antiinflammatory and antimicrobial effects in vitro [45,46].…”

Section: Recent Publications On the Ginger Familymentioning

confidence: 99%

Polyploidy in the Ginger Family from Thailand

Anamthawat‐Jónsson¹,

Umpunjun²

2020

Chromosomal Abnormalities

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Polyploidy is common in the ginger family Zingiberaceae. The aims of the present paper are (1) to provide a general introduction on species diversity with emphasis on conservation; (2) to highlight the human-use significance of this family, focusing on the two major genera, Zingiber (ginger) and Curcuma (turmeric); (3) to present chromosome number data from 45 natural and cultivated Curcuma taxa from Thailand, of which polyploids are predominant; and (4) to describe our own work on cytotaxonomy of selected Thai Curcuma species. We obtained somatic chromosome numbers from root tips and analysed meiotic chromosome behaviour from flowers. We also used the molecular cytogenetic method of ribosomal gene mapping on chromosomes to infer mechanism of polyploidization and reveal genomic relationships among closely related species. The main results of our cytogenetic studies include the following. The most sought-after medicinal Curcuma cultivars growing on a large-scale basis are secondary triploids, so as taxa in natural habitats that are harvested for local utilisation. These triploids are sexually deficient, due to meiotic pairing abnormalities, but they are propagated asexually via rhizomes. The ribosomal mapping results indicate natural triploidization process via hybridisation, either within populations or across the species boundaries.

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Section: Recent Publications On the Ginger Familymentioning

confidence: 99%

Polyploidy in the Ginger Family from Thailand

Anamthawat‐Jónsson¹,

Umpunjun²

2020

Chromosomal Abnormalities

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“…Curcumin is a yellow pigment derived from the C.longa plant, is a principal component of turmeric, and is widely used as a spice and culinary color [1]. Antioxidant, chemopreventive, proapoptotic, antiinflammatory, antifungal, anti-ischemic, hepatoprotective, antiparasitic, antimicrobial, and chemotherapeutic activity are all present [2,3]. Although curcumin has several advantages, it suffers from limited bioavailability after oral administration [4].…”

Section: Introductionmentioning

confidence: 99%

The Drying Temperature Impact on Curcumin - Piperine Dissolution and Its Kinetic Release: Application of A Spray Dryer on the Preparation of Solid Dispersion-based Microparticle Containing Curcuma longa and Piper Nigrum Extracts

Ayu PURNAMASARI,

SETYANINGSIH

2023

jrp

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The Effectiveness of Mucoadhesive and Mouthwash Therapy for Oral Mucositis With Synthetic and Herbal Ingredients: A Systematic Review and Meta-Analysis

KARINA,

SUFIAWATI,

RAMAMOORTHY

2024

Int J App Pharm

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This study aimed to evaluate the effectiveness of herbal and synthetic mucoadhesive formulations and mouthwashes to reduce the grade and pain of Oral Mucositis (OM) through a systematic review and meta-analysis. Selection of articles published between 2014 and 2023 using Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) with specific keywords and through electronic databases (PubMed, Cochrane, Scopus, and Google Scholar) was carried out. Inclusion and exclusion criteria were established to limit the search for articles. The quality assessment of the articles used the Oxford Quality Scoring System. All 22 articles could be assessed by systematic review, but only 16 articles could be meta-analysis. The meta-analysis assessment used Jeffreys's Amazing Statistics Program (JASP) software. The mucoadhesive formulations of 1% Satureja hortensis extract gel, phenytoin tablets, 3% Chamomile topical gel and the mouthwash consisting morphine 2%, povidone-iodine 10 ml, turmeric, dentoxol, zinc chloride, sodium bicarbonate had affected to reduce the degree and pain of OM. Meta-analysis showed mucoadhesive had a mean effect size of -0.06 on the grade and -0.12 on the pain of the OM, while mouthwash had a mean effect size of -1.27 on the grade and -1.64 on the pain of the OM. To conclude, mucoadhesive formulations and mouthwashes have the potential to reduce the grade and pain of OM.

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Reduction of salivary tumor necrosis factor alpha levels in response to magic mouthwash with Curcuma xanthorriza in cancer patients undergoing chemotherapy

Abstract: salivary tumor necrosis factor alpha levels in response to magic mouthwash with Curcuma xanthorriza in cancer patients undergoing chemotherapy.

Cited by 3 publications

References 19 publications

Polyploidy in the Ginger Family from Thailand

Polyploidy in the Ginger Family from Thailand

The Drying Temperature Impact on Curcumin - Piperine Dissolution and Its Kinetic Release: Application of A Spray Dryer on the Preparation of Solid Dispersion-based Microparticle Containing Curcuma longa and Piper Nigrum Extracts

The Effectiveness of Mucoadhesive and Mouthwash Therapy for Oral Mucositis With Synthetic and Herbal Ingredients: A Systematic Review and Meta-Analysis

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