Reduction of product composition variability using pooled microbiome ecosystem therapy and consequence in two infectious murine models
Julie Reygner,
Johanne Delannoy,
Marie-Thérèse Barba-Goudiaby
et al.
Abstract:Growing evidence demonstrates the key role of the gut microbiota in human health and disease. The recent success of microbiotherapy products to treat recurrent
Clostridioides difficile
infection has shed light on its potential in conditions associated with gut dysbiosis, such as acute graft-versus-host disease, intestinal bowel diseases, neurodegenerative diseases, or even cancer. However, the difficulty in defining a “good” donor as well as the intrinsic variability of donor-derive… Show more
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