Reduction of polyatomic ion interferences in inductively coupled plasma mass spectrometry with cryogenic desolvation

Abstract

INTRODUCTION 11 EXPERIMENTAL SECTION Instrumentation Desolvation Procedures Data Acquisition Standard Solutions RESULTS AND DISCUSSION 19 Desolvation and Plasma Characteristics 19 Background Mass Spectra and Removal of C10+, ArCl+, and ArO+ REMOVAL OF METAL OXIDES

Fundamental studies on droplet throughput and the analysis of single cells using a downward-pointing ICP-time-of-flight mass spectrometer

“…improved sensitivity or reduction of polyatomic ion interferences when heated. [45][46][47][48][49][50][51] For example, in Mass Cytometry (MC), the CyTOF® instruments are equipped with heated spray chambers operating at temperatures up to 200 C. 52,53 The system has proven itself as very practical for single cell analysis. In certain elds of application, MC has truly become a competing technique to Flow Cytometry (FC).…”