“…The antimicrobial action of the active compounds is affected not only by the target microorganisms, but also by a wide number of factors associated to the food composition, such as pH, water activity, fat and protein contents, or its nature microflora . Many antimicrobials (such as chitosan, nisin, LAE and -polylysine) have been tested against Listeria in salmon and, in spite of the numerous studies demonstrating their efficacy in other food products, such as fresh cheese (Soni et al, 2012), cured ham (Stopforth et al, 2010) and Frankfurt style sausages (Martin et al, 2010), antilisterial activity has not been found when directly applied to salmon. This has been attributed to the effective distribution of the antimicrobial compound in the fat phase of the fish, thus reducing its availability for antimicrobial action .…”