Reduction of foot-and-mouth disease virus transmission in cattle vaccinated one or two weeks before challenge using a commercial polyvalent vaccine

Duffy, Sergio; Fondevila, Norberto; Novo, Sabrina Galdo; Aznar, Maria Natalia; Garro, Carlos; Smitsaart, Eliana; Monti, Gustavo

doi:10.1016/j.jvacx.2020.100063

Cited by 1 publication

(1 citation statement)

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“…The guidelines require that 12 out of 16 vaccinated animals (75%) be protected (Saad and Deghaidy, 2012) [2]. However, other challenge experiments have been conducted using groups of 5 animals only to evaluate immunogenicity, potency and cross challenge studies before batch release [6,7].…”

Section: Introductionmentioning

confidence: 99%

Comments on Sequence Analysis of Egyptian Foot-and-Mouth Disease Virus Field and Vaccine Strains: Intertypic Recombination and Evidence for Accidental Release.

Wasfy¹

2021

NIDOC-ASRT

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Egyptian Journal of Veterinary Sciences https://ejvs.journals.ekb.eg/ 27 M OLECULAR epidemiology research on foot-and-mouth disease (FMD) viruses typically requires information on the study population and a sufficient number of samples for accurate detection and trending of serotypes and lineages in a region or country. Based on the study of Abdel Rahman et al. [1], this commentary is to draw the attention to insufficient sample size and limited geographical locations that represent the circulating field strains of foot-and-mouth disease (FMD) virus in Egypt during 2016. Sequence analysis of one FMD vaccine sample produced locally in 2019 was compared to circulating strains in 2016, irrespective of time difference. While the epidemiological circumstances were different, the results showed absence of some viral vaccine antigens and suggested intertypic recombination and accidental virus release. These results may be associated with compromised sensitivities of the methods employed, irrelevant quality control procedures and improbable or far-fetched speculations. Also, anonymity of the analyzed product casts doubts on all locally produced vaccines in Egypt.

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Section: Introductionmentioning

confidence: 99%

Comments on Sequence Analysis of Egyptian Foot-and-Mouth Disease Virus Field and Vaccine Strains: Intertypic Recombination and Evidence for Accidental Release.

Wasfy¹

2021

NIDOC-ASRT

View full text Add to dashboard Cite

show abstract

Reduction of foot-and-mouth disease virus transmission in cattle vaccinated one or two weeks before challenge using a commercial polyvalent vaccine

Cited by 1 publication

References 19 publications

Comments on Sequence Analysis of Egyptian Foot-and-Mouth Disease Virus Field and Vaccine Strains: Intertypic Recombination and Evidence for Accidental Release.

Comments on Sequence Analysis of Egyptian Foot-and-Mouth Disease Virus Field and Vaccine Strains: Intertypic Recombination and Evidence for Accidental Release.

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