Reduction of cytotoxicity of Myramistin by adsorption on nanodiamonds

Chernysheva, Maria G.; Melik‐Nubarov, N. S.; Grozdova, Irina D.; Myasnikov, Ivan Yu.; Tashlitsky, Vadim N.; Badun, G. A.

doi:10.1016/j.mencom.2017.07.036

Cited by 18 publications

(1 citation statement)

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The route of entry into cancer cells is primarily determined by the material of the nanoparticle. Currently, the following nanoforms are used as nanoscale carriers for drugs ( Figure 5 ): Biological and biogenic nanoparticles (enzymes, proteins, ribosomes, and viruses) [ 47 , 48 , 49 ]; Polymer nanoparticles and nanostructures (polymer nanoparticles, polymer nanocapsules, polymer micelles, and dendrimers [ 50 , 51 , 52 ]; Liposomes [ 53 ]; Perfluorocarbon nanoparticles [ 54 , 55 ]; Carbon nanoparticles (nanotubes, fullerenes, graphene, and nanodiamonds) [ 56 , 57 , 58 ]; Inorganic nanoparticles (metals such as gold, silver, platinum, titanium, zinc, and iron; metal and nonmetal oxides; and magnetic nanoparticles) [ 59 , 60 , 61 , 62 , 63 ]; Quantum dots and semiconductor nanocrystals [ 64 , 65 ]. …”

Section: Application Of Micro- and Nanoparticles In Drug Delivery Sys...mentioning

confidence: 99%

Surface Modification of Mesoporous Silica Nanoparticles for Application in Targeted Delivery Systems of Antitumour Drugs

Kovtareva,

Kusepova,

Tazhkenova

et al. 2024

Polymers

View full text Add to dashboard Cite

The problem of tumour therapy has attracted the attention of many researchers for many decades. One of the promising strategies for the development of new dosage forms to improve oncology treatment efficacy and minimise side effects is the development of nanoparticle-based targeted transport systems for anticancer drugs. Among inorganic nanoparticles, mesoporous silica deserves special attention due to its outstanding surface properties and drug-loading capability. This review analyses the various factors affecting the cytotoxicity, cellular uptake, and biocompatibility of mesoporous silica nanoparticles (MSNs), constituting a key aspect in the development of safe and effective drug delivery systems. Special attention is paid to technological approaches to chemically modifying MSNs to alter their surface properties. The stimuli that regulate drug release from nanoparticles are also discussed, contributing to the effective control of the delivery process in the body. The findings emphasise the importance of modifying MSNs with different surface functional groups, bio-recognisable molecules, and polymers for their potential use in anticancer drug delivery systems.

show abstract