Reduction in Cannabis Use and Functional Status in Physical Health, Mental Health, and Cognition

Mooney, Larissa; Zhu, Yuhui; Yoo, Caroline; Valdez, Jonathan; Moino, Kevin; Liao, Jung‐Yu; Hser, Yih‐Ing

doi:10.1007/s11481-018-9813-6

Cited by 19 publications

(7 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…These symptoms may be mistaken for an exacerbation of depression. On the other hand, some studies show that a reduction in CU and cannabis abstinence are associated with improvements in anxiety, depression and functioning in individuals with problematic CU (14,94). As such, these observations are consistent with the idea that mood symptoms may be secondary (not antecedent) to CU.…”

Section: Effects Of Cessation Of Cannabis Usesupporting

confidence: 65%

Down and High: Reflections Regarding Depression and Cannabis

et al. 2021

View full text Add to dashboard Cite

In light of the recent changes in the legal status of cannabis in Canada, the understanding of the potential impact of the use of cannabis by individuals suffering from depression is increasingly considered as being important. It is fundamental that we look into the existing literature to examine the influence of cannabis on psychiatric conditions, including mood disorders. In this article, we will explore the relationship that exists between depression and cannabis. We will examine the impact of cannabis on the onset and course of depression, and its treatment. We have undertaken a wide-ranging review of the literature in order to address these questions. The evidence from longitudinal studies suggest that there is a bidirectional relationship between cannabis use and depression, such that cannabis use increases the risk for depression and vice-versa. This risk is possibly higher in heavy users having initiated their consumption in early adolescence. Clinical evidence also suggests that cannabis use is associated with a worse prognosis in individuals with major depressive disorder. The link with suicide remains controversial. Moreover, there is insufficient data to determine the impact of cannabis use on cognition in individuals with major depression disorder. Preliminary evidence suggesting that the endogenous cannabinoid system is involved in the pathophysiology of depression. This will need to be confirmed in future positron emission tomography studies. Randomized controlled trials are needed to investigate the potential efficacy of motivational interviewing and/or cognitive behavioral therapy for the treatment of cannabis use disorder in individuals with major depressive major disorder. Finally, although there is preclinical evidence suggesting that cannabidiol has antidepressant properties, randomized controlled trials will need to properly investigate this possibility in humans.

show abstract

Section: Effects Of Cessation Of Cannabis Usesupporting

confidence: 65%

Down and High: Reflections Regarding Depression and Cannabis

et al. 2021

View full text Add to dashboard Cite

show abstract

“…For example, replacing high-potency cannabis with CBD-rich cannabis would mean a reduction in THC exposure while preserving the gesture and the sensory dimensions of cannabis use. This reduction would likely reduce anxiety and depression in people with cannabis use disorder ( 33 , 34 ), and be an acceptable and therefore achievable treatment goal for treatment-seeking users ( 35 ). Such a reduction in exposure to THC may also lead to cannabis abstinence.…”

Section: Discussionmentioning

confidence: 99%

A “Good” Smoke? The Off-Label Use of Cannabidiol to Reduce Cannabis Use

Fortin¹,

Beo

Massin

et al. 2022

Front. Psychiatry

View full text Add to dashboard Cite

BackgroundAlthough cannabis use is common in France, it is still criminalized. Cannabidiol (CBD) products, including CBD-rich cannabis, are legally available. Although previous results suggested that CBD may have benefits for people with cannabis use disorder, there is a lack of data on cannabis users who use CBD to reduce their cannabis consumption. We aimed to identify (i) correlates of this motive, and (ii) factors associated with successful attempts to reduce cannabis use.MethodsA cross-sectional online survey among French-speaking CBD and cannabis users was conducted. Logistic regressions were performed to identify correlates of using CBD to reduce cannabis consumption and correlates of reporting a large reduction.ResultsEleven percent (n = 105) of our study sample reported they primarily used CBD to reduce cannabis consumption. Associated factors included smoking tobacco cigarettes (adjusted odds ratio (aOR) [95% confidence interval (CI)] 2.17 [1.3–3.62], p = 0.003) and drinking alcohol (aOR [95%CI] 1.8 [1.02–3.18], p = 0.042). Of these 105, 83% used CBD-rich cannabis to smoke, and 58.7% reported a large reduction in cannabis consumption. This large reduction was associated with non-daily cannabis use (aOR [95%CI] 7.14 [2.4–20.0], p < 0.001) and daily CBD use (aOR [95%CI] 5.87 [2.09–16.47], p = 0.001). A reduction in cannabis withdrawal symptoms thanks to CBD use was the most-cited effect at play in self-observed cannabis reduction.ConclusionsCannabis use reduction is a reported motive for CBD use—especially CBD-rich cannabis to smoke—in France. More studies are needed to explore practices associated with this motive and to accurately assess CBD effectiveness.

show abstract

“…Along with its potential therapeutic benefits, adverse effects from cannabis use have been documented, such as neurocognitive deterioration including memory impairment [15,16,[20][21][22][23][24][25]. What is also likely is cannabis use in children and young adults carry a higher risk for long-term deficits [25].…”

Section: Introductionmentioning

confidence: 99%

Medical Students’ Attitudes, Knowledge, and Beliefs about Medical Cannabis: A Qualitative Descriptive Study

Jacobs¹,

Colon²,

Kane³

2022

Cureus

View full text Add to dashboard Cite

BackgroundThere has been increased attention given to understanding the uses of medical cannabis (MC) for symptom management of various medical conditions. Physicians receive minimal training in medical school and rely mostly on anecdotal evidence; by proxy, medical students generally do receive formal training in MC. It is unknown how medical students perceive MC, including its efficacy, appropriateness in medicine, its possible adverse effects, and its value for patients. This study investigated medical students' perceived knowledge, beliefs, and attitudes toward MC to better understand their knowledge about and attitudes toward MC. MethodUsing a semi-structured interview guide, eight focus groups were conducted with 83 medical students via Zoom virtual meeting platform (Zoom Video Communications, Inc., San Jose, California, United States) in June 2022. The interviews were guided by the following content areas: (1) beliefs about cannabis' therapeutic utility, (2) perceived knowledge about MC, (3) the role of the physician regarding MC, (4) concern for cannabis' adverse effects, and (5) MC education in the school curriculum. Data were analyzed using thematic analysis, an iterative, systematic process of coding patterns, and emerged themes in the interview data to explore medical students' perceptions about MC. Themes were validated based on whether each theme captured distinct parts of the interview data and whether their content cohered meaningfully. ResultsFour themes emerged from the focus group interviews investigating medical students' perceptions of MC:(1) erroneous beliefs about MC, (2) unreliable sources of information, (3) mixed attitudes toward legalization, and (4) desire for MC education while in medical school. Attitudes regarding MC in general, including legalization, varied by United States state of origin of the student and exposure to MC (e.g., use by family member). ConclusionMC seems to be a significant issue for medical trainees who might be required to recommend it to patients and manage coexisting therapies. Cultivating new knowledge about students' perceptions and perceived knowledge about medicinal options and dosing of MC is critical for medical educators as they design undergraduate curricular initiatives for future physicians.

show abstract

Reduction in Cannabis Use and Functional Status in Physical Health, Mental Health, and Cognition

Cited by 19 publications

References 25 publications

Down and High: Reflections Regarding Depression and Cannabis

Down and High: Reflections Regarding Depression and Cannabis

A “Good” Smoke? The Off-Label Use of Cannabidiol to Reduce Cannabis Use

Medical Students’ Attitudes, Knowledge, and Beliefs about Medical Cannabis: A Qualitative Descriptive Study

Contact Info

Product

Resources

About