“…7 In addition to the use of CG to control orthodontic pain, topical anesthetics confirmed to be very effective in reducing or eliminating pain associated with needle stick injections, suturing of facial lacerations, and different orthodontic procedures. [8][9][10][11][12][13][14][15][16] More recently, a study shows that the lidocaine/prilocaine (L/P) gel can significantly reduce pain from immediate placement of orthodontic elastomeric separators. 17 Medicated CG is an effective drug delivery system intended for either local or systemic treatment.…”
Aim:The aim of this study was to investigate the effect of a formulated anesthetic chewing gum (ACG) on the initial pain/discomfort resulting from the placement of orthodontic separators. Materials and methods: The preparation of ACG formulation was investigated using food and drug administration (FDA)-certified ingredients. Sixty subjects were recruited and randomly allocated to three groups: (1) ACG, (2) chewing gum (CG) without anesthetics or (3) control (no CG) group. All subjects received an orthodontic elastomeric separator that was placed between the maxillary right or left first molar and second premolar. For all groups, the registration of pain/discomfort experienced immediately after separator placement (0 hour), then after 1, 4, and 8 hours was carried out using the visual analog scale. Results: Regarding the pain/discomfort perception, there was a statistically significant difference (p value <0.0001) between the three groups (ACG, CG, and controls) at each of the three-time points (1, 4 and 8 hours). There were no harms reported by both groups except for temporary mild muscle soreness from gum chewing that was reported by four subjects from the ACG group and two subjects from the CG group.
Conclusion:The ACG can significantly decrease and eliminate the initial pain/discomfort resulting from the placement of the orthodontic elastomeric separators. Furthermore, the ACG may decrease the need for a systemic analgesic. Clinical significance: Orthodontic elastomeric separator placement can be uncomfortable. The ACG significantly decreased the initial pain/ discomfort from orthodontic separators during the 8 hours. Therefore, the ACG can be used by the patients as needed whenever pain/discomfort is experienced from the placement of elastomeric separators. Consequently, this may reduce the need for systemic analgesics.
“…7 In addition to the use of CG to control orthodontic pain, topical anesthetics confirmed to be very effective in reducing or eliminating pain associated with needle stick injections, suturing of facial lacerations, and different orthodontic procedures. [8][9][10][11][12][13][14][15][16] More recently, a study shows that the lidocaine/prilocaine (L/P) gel can significantly reduce pain from immediate placement of orthodontic elastomeric separators. 17 Medicated CG is an effective drug delivery system intended for either local or systemic treatment.…”
Aim:The aim of this study was to investigate the effect of a formulated anesthetic chewing gum (ACG) on the initial pain/discomfort resulting from the placement of orthodontic separators. Materials and methods: The preparation of ACG formulation was investigated using food and drug administration (FDA)-certified ingredients. Sixty subjects were recruited and randomly allocated to three groups: (1) ACG, (2) chewing gum (CG) without anesthetics or (3) control (no CG) group. All subjects received an orthodontic elastomeric separator that was placed between the maxillary right or left first molar and second premolar. For all groups, the registration of pain/discomfort experienced immediately after separator placement (0 hour), then after 1, 4, and 8 hours was carried out using the visual analog scale. Results: Regarding the pain/discomfort perception, there was a statistically significant difference (p value <0.0001) between the three groups (ACG, CG, and controls) at each of the three-time points (1, 4 and 8 hours). There were no harms reported by both groups except for temporary mild muscle soreness from gum chewing that was reported by four subjects from the ACG group and two subjects from the CG group.
Conclusion:The ACG can significantly decrease and eliminate the initial pain/discomfort resulting from the placement of the orthodontic elastomeric separators. Furthermore, the ACG may decrease the need for a systemic analgesic. Clinical significance: Orthodontic elastomeric separator placement can be uncomfortable. The ACG significantly decreased the initial pain/ discomfort from orthodontic separators during the 8 hours. Therefore, the ACG can be used by the patients as needed whenever pain/discomfort is experienced from the placement of elastomeric separators. Consequently, this may reduce the need for systemic analgesics.
“…It should be applied from triage for 30 min when no contraindication is present (large, profound or contaminated laceration, mucosa, allergies, age \3 months, and extremities such as the nose and ears) [27,129,130,133]. A meta-analysis found that several cocaine-free topical anesthetics provided effective analgesia, but many trials were at high risk of bias, reducing the strength of the conclusions [134].…”
Far more attention is now given to pain management in children in the emergency department (ED). When a child arrives, pain must be recognized and evaluated using a pain scale that is appropriate to the child's development and regularly assessed to determine whether the pain intervention was effective. At triage, both analgesics and non-pharmacological strategies, such as distraction, immobilization, and dressing should be started. For mild pain, oral ibuprofen can be administered if the child has not received it at home, whereas ibuprofen and paracetamol are suitable for moderate pain. For patients who still require pain relief, oral opioids could be considered; however, many EDs have now replaced this with intranasal fentanyl, which allows faster onset of pain relief and can be administered on arrival pending either intravenous access or definitive care. Intravenous opioids are often required for severe pain, and paracetamol or ibuprofen can still be considered for their likely opioid-sparing effects. Specific treatment should be used for patients with migraine. In children requiring intravenous access or venipuncture, non-pharmacological and pharmacological strategies to decrease pain and anxiety associated with needle punctures are mandatory. These strategies can also be used for laceration repairs and other painful procedures. Despite the gaps in knowledge, pain should be treated with the most up-to-date evidence in children seen in EDs.
“…Despite the existence of these topical anesthetics, in the management of wounds for pain control, infiltrated anesthetics have traditionally been used [ 5 ], requiring a painful injection for anesthesia. However, in some cases, these can be avoided, or carried out without pain, by treating the area to be infiltrated using a topical anesthetic [ 6 ]. These topical anesthetics have been used as a treatment for the reduction of pain in wounds since the second half of the 19th century, with the discovery of cocaine [ 7 ].…”
The treatment of dermal injuries is associated with pain in both adult and pediatric populations. We reviewed traditional treatments for controlling the pain of these lesions, such as infiltrated local anesthetics and topical local anesthetics. The objective of this review was to elucidate the efficacy of topical anesthetics in reducing the pain of dermal injuries, as well as the efficacy of topical anesthetics versus other anesthetics, or versus a placebo. Methodology: a systematic review was carried out by searching Medline (PubMED), Scopus, Cinahl, Cochrane, Lilacs, and ENFISPO for randomized clinical trials on the control of pain in dermal lesions through the use of topical anesthetics, versus a placebo or versus another anesthetic. Results: twelve randomized clinical trials with a total of 952 patients were included. Seven studies analyzed the efficacy of topical anesthetics compared to a placebo, and six of them observed statistically significant differences in favor of the experimental group. Five studies analyzed the efficacy of topical anesthetics compared to other anesthetics or sedatives; three of them observed statistically significant differences in favor of the experimental group, and two found no difference between the anesthetics analyzed. Conclusion: topical anesthesia is a useful method for pain control, is safe compared to other traditional methods, and offers a satisfactory form of pain relief in relation to infiltration anesthesia and compared to placebo.
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