Reducing the Burden of Anemia in Infants and Young Children in Malaria-Endemic Countries of Africa: From Evidence to Action

Crawley, Jane

doi:10.4269/ajtmh.2004.71.25

Cited by 227 publications

(218 citation statements)

References 135 publications

(145 reference statements)

Supporting

Mentioning

206

Contrasting

Unclassified

Order By: Relevance

“…Anaemia, (Hb<11.0g/dl) was found to be present in 23.2% of the pregnant women in this study, of which 92.8% had mild anemia (Hb 9-10g/dl), 6.3% had moderate anaemia (Hb 7.0-8.9g/dl) and 0.9% had severe anaemia (Hb<7.0g/dl). This finding is contrary to the 79.1% overall prevalence found among pregnant first-time attenders in Calabar [1].…”

Section: Discussionmentioning

confidence: 45%

See 1 more Smart Citation

Prevalence and Risk Factors of Anaemia Among Pregnant women in Nigeria

Buseri¹,

Uko²,

Jeremiah³

et al. 2008

TOHJ

View full text Add to dashboard Cite

Abstract:To assess the prevalence and risk factors of anaemia in pregnancy and recommend a cut-off value for antenatal women in developing countries, a cross sectional study was carried in the University of Port Harcourt Teaching Hospital, Port Harcourt, a 523 bed tertiary health care institution in Nigeria. 1371 apparently healthy asymptomatic pregnant women visiting the antenatal clinic for the first time were enrolled for the study. Another 60 age-matched non-pregnant apparently healthy women served as controls. Haemoglobin concentration, malaria, human immunodeficiency virus (HIV)S, haemoglobin electrophoretic pattern and C-reactive protein as marker of infection were investigated using standard haematological and serological procedures. Anaemia in pregnancy (Hb <11.0g/dl) and (Hb<10.0g/dl) were found to be 23.2% and 6.7% respectively. The aetiology of anaemia was found to be multifactorial; 40.2% had anaemia of infection, 20.3% had Plasmodium falciparum alone, 8.5% had HIV alone, 2.5% had HIV and malaria parasite co-infection; 8.9% undetermined infections and 0.6% had sickle cell anaemia. There is moderate prevalence of anaemia in pregnancy in this part of the world. Since the mean Hb value of the pregnant women in this study was 11.62±1.21g/dl and the pregnant women with Hb values around 10g/dl are apparently healthy, a cut-off value of 10.0g/dl may be considered ideal for defining anaemia in pregnancy in developing countries.

show abstract

Section: Discussionmentioning

confidence: 45%

“…It is extremely common and although not always shown to have a causal link, severe anaemia contributes to maternal morbidity and mortality [1][2][3][4][5][6]. Anaemia, even when mild to moderate affects the sense of well-being resulting in fatigue, stress and reduced work productivity [7].…”

Section: Introductionmentioning

confidence: 99%

Prevalence and Risk Factors of Anaemia Among Pregnant women in Nigeria

Buseri¹,

Uko²,

Jeremiah³

et al. 2008

TOHJ

View full text Add to dashboard Cite

show abstract

“…= 3, P = 0.003). Anaemia, defined as haemoglobin <11 g/dl (Crawley, 2004), was recorded in 909 children (34.4%), the prevalence of which was not significantly associated with sex (boys 35.2% vs. girls 34.3%; 2 = 0.27, d.f. = 1, P = 0.605), but it decreased significantly with age (age 6 years, 42.2%; age 7 years, 38.3%; age 8 years, 34.2%; age 11 years, 25.4%; 2 = 44.58, d.f.…”

Section: Study Compliance and Operational Resultsmentioning

confidence: 95%

Morbidity due to Schistosoma mansoni: an epidemiological assessment of distended abdomen syndrome in Ugandan school children with observations before and 1-year after anthelminthic chemotherapy

Balen

Stothard

Kabatereine

et al. 2006

Transactions of the Royal Society of Tropical Medicine and Hygi

View full text Add to dashboard Cite

show abstract

“…In the absence of iron supplementation, over 50% of infants in resource-poor countries develop iron deficiency anaemia by the age of 6 months (van Eijk et al, 2002;Schellenberg et al, 2003;Crawley, 2004). Iron deficiency anaemia is associated with increased mortality (Brabin et al, 2001;Brabin et al, 2003), and has been related to impaired mental and motor development (GranthamMcGregor and Ani, 2001).…”

Section: Introductionmentioning

confidence: 99%

A cohort study of haemoglobin and zinc protoporphyrin levels in term Zambian infants: effects of iron stores at birth, complementary food and placental malaria

et al. 2007

View full text Add to dashboard Cite

Objective: To examine zinc-protoporphyrin (ZPP) and haemoglobin levels, and to determine predictors of iron deficiency anaemia (IDA) in Zambian infants. Subjects and methods: Ninety-one women and their normal birth weight (NBW) infants were followed bi-monthly during the first 6 months of life, and iron status, food intake, malaria parasitaemia and growth were monitored. At 4 months, the infants were divided into two groups, and the data were analysed according to whether or not they were exclusively breastfed. Results: Almost two-third of infants were born with low iron stores as defined by ZPP levels, and this proportion increased with age. Over 50% had developed IDA by 6 months. Exclusive breastfeeding at 4 months could be a protective factor for IDA (odds ratio (OR): 0.2; 95% confidence interval (CI): 0.0-1.1). Exclusively breastfed infants had higher haemoglobin values at 4 and 6 months (mean difference 0.6; 95% CI: 0.1-1.2 g/dl and mean difference 0.9; 95% CI: 0.2-1.7 g/dl, respectively), compared with infants with early complementary feeding. In univariate analysis, past or chronic placental malaria appeared to be a predictor of IDA at 4 and 6 months, but the significance was lost in multivariate analysis. Conclusions: Zambian NBW infants are born with low iron stores and have a high risk to develop IDA in the first 6 months of life. Continuation of exclusive breastfeeding after 4 months is associated with a reduction of anaemia. The effect of placental malaria infection on increased risk of infant IDA could not be proven.

show abstract

Reducing the Burden of Anemia in Infants and Young Children in Malaria-Endemic Countries of Africa: From Evidence to Action

Cited by 227 publications

References 135 publications

Prevalence and Risk Factors of Anaemia Among Pregnant women in Nigeria

Prevalence and Risk Factors of Anaemia Among Pregnant women in Nigeria

Morbidity due to Schistosoma mansoni: an epidemiological assessment of distended abdomen syndrome in Ugandan school children with observations before and 1-year after anthelminthic chemotherapy

A cohort study of haemoglobin and zinc protoporphyrin levels in term Zambian infants: effects of iron stores at birth, complementary food and placental malaria

Contact Info

Product

Resources

About