Reducing systematic review burden using Deduklick: a novel, automated, reliable, and explainable deduplication algorithm to foster medical research

Borissov, Nikolay; Haas, Quentin; Minder, Beatrice; Kopp‐Heim, Doris; Gernler, Marc von; Janka, Heidrun; Teodoro, Douglas; Amini, Poorya

doi:10.1186/s13643-022-02045-9

Cited by 35 publications

(26 citation statements)

References 21 publications

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“…While deduplication can be conducted manually, nowadays standard bibliographic management software and specialized tools provide automated deduplication solutions, allowing for easier and faster processing. 35 42 43…”

Section: Resultsmentioning

confidence: 99%

The TARCiS statement: Guidance on terminology, application, and reporting of citation searching

Hirt,

Nordhausen,

Fuerst

et al. 2023

Preprint

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Evidence syntheses adhering to systematic literature searching techniques are a cornerstone of evidence-based health care. Beyond term-based searching in electronic databases, citation searching is a prevalent search technique to identify relevant sources of evidence. However, for decades, citation searching methodology and terminology has not been standardized. We performed an evidence-guided four-round Delphi consensus study with 27 international methodological experts in order to develop the Terminology, Application, and Reporting of Citation Searching (TARCiS) statement. TARCiS comprises ten specific recommendations on when and how to conduct and report citation searching in the context of systematic literature searches and four research priorities. We encourage systematic reviewers and information specialists to incorporate TARCiS into their standardized workflows.

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Section: Resultsmentioning

confidence: 99%

The TARCiS statement: Guidance on terminology, application, and reporting of citation searching

Hirt,

Nordhausen,

Fuerst

et al. 2023

Preprint

View full text Add to dashboard Cite

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“…Literature published in English was considered. Duplicate records were removed with Deduklick [ 17 ]. The search strategy is described in detail in Table S2 .…”

Section: Methodsmentioning

confidence: 99%

Non-Specific Effects of Bacillus Calmette-Guérin: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Trunk¹,

Davidović

Bohlius

2023

Vaccines

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Background: Vaccines induce antigen-specific immunity, which provides long-lived protection from the target pathogen. Trials from areas with high incidence rates for infectious diseases indicated that the tuberculosis vaccine Bacillus Calmette-Guérin (BCG) induces in addition non-specific immunity against various pathogens and thereby reduces overall mortality more than would have been expected by just protecting from tuberculosis. Although recent trials produced conflicting results, it was suggested that BCG might protect from non-tuberculosis respiratory infections and could be used to bridge the time until a specific vaccine against novel respiratory diseases like COVID-19 is available. Methods: We performed a systematic search for randomized controlled trials (RCTs) published between 2011 and December 9th, 2022, providing evidence about non-specific effects after BCG vaccination, assessed their potential for bias, and meta-analyzed relevant clinical outcomes. We excluded RCTs investigating vaccination with an additional vaccine unless outcomes from a follow-up period before the second vaccination were reported. Results: Our search identified 16 RCTs including 34,197 participants. Vaccination with BCG caused an estimated 44% decrease in risk for respiratory infections (hazard ratio (HR) 0.56, 95% confidence interval (CI) 0.39–0.82) with substantial heterogeneity between trials (I2 = 77%). There was evidence for a protective effect on all-cause mortality of 21% if follow-up was restricted to one year (HR 0.79, 95% CI 0.64–0.99). We did not find evidence for an effect when we considered longer follow-up (HR 0.88, 95% CI 0.75–1.03). Infection-related mortality after BCG vaccination was reduced by 33% (HR 0.67; 95% CI 0.46–0.99), mortality for sepsis by 38% (HR 0.62, 95% CI 0.41–0.93). There was no evidence for a protective effect of BCG vaccination on infections of any origin (HR 0.84, 95% CI 0.71–1.00), COVID-19 (HR 0.88, 95% CI 0.68–1.14), sepsis (HR 0.78, 95% CI 0.55–1.10) or hospitalization (HR 1.01, 95% CI 0.91–1.11). Conclusions: According to these results, depending on the setting, vaccination with BCG provides time-limited partial protection against non-tuberculosis respiratory infections and may reduce mortality. These findings underline BCG’s potential (1) in pandemic preparedness against novel pathogens especially in developing countries with established BCG vaccination programs but limited access to specific vaccines; (2) in reducing microbial infections, antimicrobial prescriptions and thus the development of antimicrobial resistance. There is a need for additional RCTs to clarify the circumstances under which BCG’s non-specific protective effects are mediated.

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“…We considered all publication dates while excluding animal studies. We removed duplicate records using Deduklicka fully automated de-duplication software (Borissov et al, 2022). Figure 1 (5) a study design with a control group or condition.…”

Section: Methodsmentioning

confidence: 99%

Brain stimulation techniques as novel treatment options for insomnia: A systematic review

Krone

Fehér

Rivero

et al. 2023

Journal of Sleep Research

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SummaryDespite the success of cognitive behavioural therapy for insomnia and recent advances in pharmacotherapy, many patients with insomnia do not sufficiently respond to available treatments. This systematic review aims to present the state of science regarding the use of brain stimulation approaches in treating insomnia. To this end, we searched MEDLINE, Embase and PsycINFO from inception to 24 March 2023. We evaluated studies that compared conditions of active stimulation with a control condition or group. Outcome measures included standardized insomnia questionnaires and/or polysomnography in adults with a clinical diagnosis of insomnia. Our search identified 17 controlled trials that met inclusion criteria, and assessed a total of 967 participants using repetitive transcranial magnetic stimulation, transcranial electric stimulation, transcutaneous auricular vagus nerve stimulation or forehead cooling. No trials using other techniques such as deep brain stimulation, vestibular stimulation or auditory stimulation met the inclusion criteria. While several studies report improvements of subjective and objective sleep parameters for different repetitive transcranial magnetic stimulation and transcranial electric stimulation protocols, important methodological limitations and risk of bias limit their interpretability. A forehead cooling study found no significant group differences in the primary endpoints, but better sleep initiation in the active condition. Two transcutaneous auricular vagus nerve stimulation trials found no superiority of active stimulation for most outcome measures. Although modulating sleep through brain stimulation appears feasible, gaps in the prevailing models of sleep physiology and insomnia pathophysiology remain to be filled. Optimized stimulation protocols and proof of superiority over reliable sham conditions are indispensable before brain stimulation becomes a viable treatment option for insomnia.

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Reducing systematic review burden using Deduklick: a novel, automated, reliable, and explainable deduplication algorithm to foster medical research

Cited by 35 publications

References 21 publications

The TARCiS statement: Guidance on terminology, application, and reporting of citation searching

The TARCiS statement: Guidance on terminology, application, and reporting of citation searching

Non-Specific Effects of Bacillus Calmette-Guérin: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Brain stimulation techniques as novel treatment options for insomnia: A systematic review

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