Reducing suicidal thoughts in the Australian general population through web-based self-help: study protocol for a randomized controlled trial

Spijker, Bregje A. J. van; Calear, Alison L.; Batterham, Philip J.; Mackinnon, Andrew; Gosling, J. A.; Kerkhof, A.J.F.M.; Solomon, Daniela; Christensen, Helen

doi:10.1186/s13063-015-0589-1

Cited by 32 publications

(17 citation statements)

References 61 publications

(64 reference statements)

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“…An additional 10 ongoing studies were identified at the time of the systematic search [ 52 – 59 ]. Further details of these ongoing trials are reported in Table 2 .…”

Section: Resultsmentioning

confidence: 99%

“… Not stated. Van Spijker, 2015 [ 59 ] RCT Australia 570 Community-dwelling adults reporting current suicidal ideation according to item five of the Columbia-Suicide Severity Rating Scale, but who do not self-report attempting suicide within the past month. iCBT: Consisting of six modules delivered once a week over a six week period.…”

Section: Resultsmentioning

confidence: 99%

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Effectiveness of online and mobile telephone applications (‘apps’) for the self-management of suicidal ideation and self-harm: a systematic review and meta-analysis

et al. 2017

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BackgroundOnline and mobile telephone applications (‘apps’) have the potential to improve the scalability of effective interventions for suicidal ideation and self-harm. The aim of this review was therefore to investigate the effectiveness of digital interventions for the self-management of suicidal ideation or self-harm.MethodsSeven databases (Applied Science & Technology; CENTRAL; CRESP; Embase; Global Health; PsycARTICLES; PsycINFO; Medline) were searched to 31 March, 2017. Studies that examined the effectiveness of digital interventions for suicidal ideation and/or self-harm, or which reported outcome data for suicidal ideation and/or self-harm, within a randomised controlled trial (RCT), pseudo-RCT, or observational pre-test/post-test design were included in the review.ResultsFourteen non-overlapping studies were included, reporting data from a total of 3,356 participants. Overall, digital interventions were associated with reductions for suicidal ideation scores at post-intervention. There was no evidence of a treatment effect for self-harm or attempted suicide.ConclusionsMost studies were biased in relation to at least one aspect of study design, and particularly the domains of participant, clinical personnel, and outcome assessor blinding. Performance and detection bias therefore cannot be ruled out. Digital interventions for suicidal ideation and self-harm may be more effective than waitlist control. It is unclear whether these reductions would be clinically meaningful at present. Further evidence, particularly with regards to the potential mechanisms of action of these interventions, as well as safety, is required before these interventions could recommended.

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“…An additional 10 ongoing studies were identified at the time of the systematic search [ 52 – 59 ]. Further details of these ongoing trials are reported in Table 2 .…”

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Effectiveness of online and mobile telephone applications (‘apps’) for the self-management of suicidal ideation and self-harm: a systematic review and meta-analysis

et al. 2017

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“…Reasons for exclusion are reported in Figure 1 . Briefly, several articles did not meet various inclusion criteria, examples of which follow: they were not interventions designed in the West and adapted for a CALD population, but instead were designed specifically for the population [ 31 - 33 ]; the participants were not considered a CALD population [ 34 - 36 ]; the interventions were not self-help according to our standard definition above [ 37 - 39 ]; and/or no common mental disorder outcome measure was reported [ 40 - 42 ].…”

Section: Resultsmentioning

confidence: 99%

Cultural Adaptation of Minimally Guided Interventions for Common Mental Disorders: A Systematic Review and Meta-Analysis

Shehadeh¹,

Heim²,

Chowdhary³

et al. 2016

JMIR Ment Health

117

121

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BackgroundCultural adaptation of mental health care interventions is key, particularly when there is little or no therapist interaction. There is little published information on the methods of adaptation of bibliotherapy and e-mental health interventions.ObjectiveTo systematically search for evidence of the effectiveness of minimally guided interventions for the treatment of common mental disorders among culturally diverse people with common mental disorders; to analyze the extent and effects of cultural adaptation of minimally guided interventions for the treatment of common mental disorders.MethodsWe searched Embase, PubMed, the Cochrane Library, and PsycINFO for randomized controlled trials that tested the efficacy of minimally guided or self-help interventions for depression or anxiety among culturally diverse populations. We calculated pooled standardized mean differences using a random-effects model. In addition, we administered a questionnaire to the authors of primary studies to assess the cultural adaptation methods used in the included primary studies. We entered this information into a meta-regression to investigate effects of the extent of adaptation on intervention efficacy.ResultsWe included eight randomized controlled trials (RCTs) out of the 4911 potentially eligible records identified by the search: four on e-mental health and four on bibliotherapy. The extent of cultural adaptation varied across the studies, with language translation and use of metaphors being the most frequently applied elements of adaptation. The pooled standardized mean difference for primary outcome measures of depression and anxiety was -0.81 (95% CI -0.10 to -0.62). Higher cultural adaptation scores were significantly associated with greater effect sizes (P=.04).ConclusionsOur results support the results of previous systematic reviews on the cultural adaptation of face-to-face interventions: the extent of cultural adaptation has an effect on intervention efficacy. More research is warranted to explore how cultural adaptation may contribute to improve the acceptability and effectiveness of minimally guided psychological interventions for common mental disorders.

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“…It compared an internet‐based cognitive–behavioral treatment program for suicidal thinking, Living with Deadly Thoughts (LwDT), and an attention‐matched control condition, Living Well. Full details of the study methodology are provided in the trial protocol (van Spijker et al., ) and primary outcomes paper (van Spijker et al., ), with a summary provided below.…”

Section: Methodsmentioning

confidence: 99%

Consistency of trajectories of suicidal ideation and depression symptoms: Evidence from a randomized controlled trial

et al. 2018

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Background: Depression is a risk factor for suicidal ideation. However, suicidal ideation can occur in the absence of depression and treating depression may not reduce suicidal thinking. This study tested whether trajectories of suicidal thinking are concordant with trajectories of depressive symptoms and sought to identify factors associated with these trajectories. Methods:Participants were community-based Australian adults (N = 418, 77% female) enrolled in a randomized controlled trial evaluating the effectiveness of an online cognitive-behavioral intervention for suicidal ideation. Separate linear growth mixture models were estimated across 12 months of follow-up to identify longitudinal trajectories of suicidal ideation and depression symptoms. Predictors of latent class membership were tested using logistic regression models.Results: Two-class models were found to have optimal fit for both suicidal thinking and depressive symptoms. Trajectory classes of suicidal ideation were: (1) moderate severity decreasing over time; and (2) high severity remaining stable over time. Depression trajectories were: (1) moderate severity with a small decrease over time; and (2) high severity that decreased moderately over time. Lower perceived burdensomeness was associated with having a greater decrease in both suicidal thinking and depression. More severe mental health symptoms were associated with less decrease in depression symptoms but not with suicidal ideation trajectory.Conclusion: Class membership across the two outcomes and predictors of class membership were found to be largely independent. The lack of coupling in trajectories and predictors suggests that changes in suicidal thinking may occur independently of changes in depression. K E Y W O R D Scognitive behavioral therapy, depression, online, suicidal ideation, trajectories

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Reducing suicidal thoughts in the Australian general population through web-based self-help: study protocol for a randomized controlled trial

Cited by 32 publications

References 61 publications

Effectiveness of online and mobile telephone applications (‘apps’) for the self-management of suicidal ideation and self-harm: a systematic review and meta-analysis

Effectiveness of online and mobile telephone applications (‘apps’) for the self-management of suicidal ideation and self-harm: a systematic review and meta-analysis

Cultural Adaptation of Minimally Guided Interventions for Common Mental Disorders: A Systematic Review and Meta-Analysis

Consistency of trajectories of suicidal ideation and depression symptoms: Evidence from a randomized controlled trial

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