Reducing medication errors involving antiretroviral therapy with targeted electronic medical record modifications

Pettit, Natasha N; Han, Zhe; Choksi, Anish; Voas-Marszowski, Donna; Pisano, Jennifer

doi:10.1080/09540121.2019.1566512

Cited by 12 publications

(12 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Pettit et al found a significant reduction in the number of patients with prescribing errors from 84/167 (50.2%) in the pre-intervention period to 37/131 (28.2%) in the post-intervention period ( p < 0.01). 32 Shawahna et al compared paper based with electronic prescribing in Pakistan in a prospective chart review. 33 They found prescribing errors differed significantly between control and intervention wards with a mean prescription errors of 21.4% and 6.9% errors respectively.…”

Section: Resultsmentioning

confidence: 99%

“…Other studies with alerts showed significant reductions in prescribing errors. 32,34 Interestingly, Shawahna et al .’s study, which comprised neither alerts nor clinical decision support, also demonstrated reduced prescription errors in intervention wards. 33 However, the effect of the intervention was more pronounced on minor errors without clinical consequences compared with those that were likely to cause patient harm.…”

Section: Discussionmentioning

confidence: 99%

“…23,51 The most common study design was a pre-post intervention design, used in 20 studies. 27,28,[30][31][32][35][36][37]40,[44][45][46][47][48][49][50][51][52][53][54] Nine studies were randomised controlled trials (RCTs. 21,[23][24][25][26]38,39,41,43 There were two quality improvement studies, 42,29 one study involved a prospective chart review with a historical control, 22 one study involved an interrupted time series design 34 and one study comprised a prospective observational design.…”

Section: Study and Patient Characteristicsmentioning

confidence: 99%

See 2 more Smart Citations

Interventions to reduce medication errors in adult medical and surgical settings: a systematic review

Manias

Kusljic

2020

Therapeutic Advances in Drug Safety

View full text Add to dashboard Cite

Background and Aims: Medication errors occur at any point of the medication management process, and are a major cause of death and harm globally. The objective of this review was to compare the effectiveness of different interventions in reducing prescribing, dispensing and administration medication errors in acute medical and surgical settings. Methods: The protocol for this systematic review was registered in PROSPERO (CRD42019124587). The library databases, MEDLINE, CINAHL, EMBASE, PsycINFO, Cochrane Database of Systematic Reviews and the Cochrane Central Register of Controlled Trials were searched from inception to February 2019. Studies were included if they involved testing of an intervention aimed at reducing medication errors in adult, acute medical or surgical settings. Meta-analyses were performed to examine the effectiveness of intervention types. Results: A total of 34 articles were included with 12 intervention types identified. Meta-analysis showed that prescribing errors were reduced by pharmacist-led medication reconciliation, computerised medication reconciliation, pharmacist partnership, prescriber education, medication reconciliation by trained mentors and computerised physician order entry (CPOE) as single interventions. Medication administration errors were reduced by CPOE and the use of an automated drug distribution system as single interventions. Combined interventions were also found to be effective in reducing prescribing or administration medication errors. No interventions were found to reduce dispensing error rates. Most studies were conducted at single-site hospitals, with chart review being the most common method for collecting medication error data. Clinical significance of interventions was examined in 21 studies. Since many studies were conducted in a pre–post format, future studies should include a concurrent control group. Conclusion: The systematic review identified a number of single and combined intervention types that were effective in reducing medication errors, which clinicians and policymakers could consider for implementation in medical and surgical settings. New directions for future research should examine interdisciplinary collaborative approaches comprising physicians, pharmacists and nurses. Lay summary Activities to reduce medication errors in adult medical and surgical hospital areas Introduction: Medication errors or mistakes may happen at any time in hospital, and they are a major reason for death and harm around the world. Objective: To compare the effectiveness of different activities in reducing medication errors occurring with prescribing, giving and supplying medications in adult medical and surgical settings in hospital. Methods: Six library databases were examined from the time they were developed to February 2019. Studies were included if they involved testing of an activity aimed at reducing medication errors in adult medical and surgical settings in hospital. Statistical analysis was used to look at the success of different types of activities. Results: A total of 34 studies were included with 12 activity types identified. Statistical analysis showed that prescribing errors were reduced by pharmacists matching medications, computers matching medications, partnerships with pharmacists, prescriber education, medication matching by trained physicians, and computerised physician order entry (CPOE). Medication-giving errors were reduced by the use of CPOE and an automated medication distribution system. The combination of different activity types were also shown to be successful in reducing prescribing or medication-giving errors. No activities were found to be successful in reducing errors relating to supplying medications. Most studies were conducted at one hospital with reviewing patient charts being the most common way for collecting information about medication errors. In 21 out of 34 articles, researchers examined the effect of activity types on patient harm caused by medication errors. Many studies did not involve the use of a control group that does not receive the activity. Conclusion: A number of activity types were shown to be successful in reducing prescribing and medication-giving errors. New directions for future research should examine activities comprising health professionals working together.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Study and Patient Characteristicsmentioning

confidence: 99%

See 1 more Smart Citation

Interventions to reduce medication errors in adult medical and surgical settings: a systematic review

Manias

Kusljic

2020

Therapeutic Advances in Drug Safety

View full text Add to dashboard Cite

show abstract

“…They also included at least 1 additional element, which ranged from education to electronic medical record (EMR) modifications. [15][16][17][18][19][20] Examples of EMR modifications included alterations to default doses and frequencies 10,15,19 and links to drug information resources. 18 All 6 studies evaluating medication errors as their primary outcome found a significant reduction in errors in the postimplementation phase.…”

Section: Resultsmentioning

confidence: 99%

“…[10][11][12][13][14] Antiretroviral stewardship programs (ARVSPs) have been shown to decrease medication error rates and improve other outcomes. [15][16][17][18][19][20] This article reviews published literature on ARVSPs and provides guidance on key aspects of ARVSPs for those looking to implement programs at their institutions.…”

Section: Introductionmentioning

confidence: 99%

Antiretroviral Stewardship: A Review of Published Outcomes with Recommendations for Program Implementation

Michienzi

Ladak

Pérez

et al. 2020

J Int Assoc Provid AIDS Care

View full text Add to dashboard Cite

Persons living with HIV (PLWHs) are at high risk for medication errors when hospitalized, but antiretroviral medications are not often evaluated by antimicrobial stewardship programs (ASPs) because they are not specifically discussed in the standards of practice. However, antiretroviral (ARV) stewardship programs (ARVSPs) have been shown to decrease medication error rates and improve other outcomes. The goal of this article is to review published literature on ARVSPs and provide guidance on key aspects of ARVSPs. A MEDLINE search using the term “antiretroviral stewardship” was conducted. Original research articles evaluating ARVSPs in hospitalized, adult PLWHs were included. Six original research articles evaluating unique inpatient ARVSPs met inclusion criteria. All 6 studies evaluating medication errors as the primary outcome found a significant reduction in errors in the postimplementation phase. Based on current standards for ASPs, we propose core elements for ARVSPs. Future organizational guidelines for antimicrobial stewardship should include official recommendations for ARV medications.

show abstract

Nurses' knowledge and implementation of antimicrobial stewardship and infection prevention strategies in acute paediatric settings

Kilpatrick

Hutchinson

Manias

et al. 2023

Journal of Hospital Infection

View full text Add to dashboard Cite

Reducing medication errors involving antiretroviral therapy with targeted electronic medical record modifications

Cited by 12 publications

References 11 publications

Interventions to reduce medication errors in adult medical and surgical settings: a systematic review

Interventions to reduce medication errors in adult medical and surgical settings: a systematic review

Antiretroviral Stewardship: A Review of Published Outcomes with Recommendations for Program Implementation

Nurses' knowledge and implementation of antimicrobial stewardship and infection prevention strategies in acute paediatric settings

Contact Info

Product

Resources

About