Reducing Blood Culture Contamination Rates: Experiences of Four Hospital Systems

Halstead, Diane; Sautter, Robert L.; Snyder, James W.; Crist, Arthur E.; Nachamkin, Irving

doi:10.1007/s40121-020-00299-1

Cited by 17 publications

(16 citation statements)

References 32 publications

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“…Because the principle of FilmArray BCID panel is PCR technology, contamination is one of the most common problems [16,17]. How to avoid contamination is also one of the aspects that need to be future improved in this detection reagent.…”

Section: Discussionmentioning

confidence: 99%

“…In the other 3 cases, the identifications of the combination method were Enterococcus spp , but Filmarray detected multiple microorganism, which may be caused by contamination during the detection process. Because the principle of FilmArray BCID panel is PCR technology, contamination is one of the most common problems[16, 17]. How to avoid contamination is also one of the aspects that need to be future improved in this detection reagent.…”

Section: Discussionmentioning

confidence: 99%

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Evaluation of the Performance of Filmarray Blood Culture Identification Panel on Detecting Blood Cultures Containing Activated Carbon Powder

Chen

Wang

2021

Preprint

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Objective: The FilmArray Blood Culture Identification (BCID) panel is a rapid microfluidic PCR amplification microbial detection system. Several studies have evaluated its clinical performance on the basis of blood culture bottles containing resins. However, proportion of hospitals in China use bottles with carbon power, which the performance of FilmArray has not been fully investigated. Therefore, this study is conducted to explore the accuracy of the panel using blood culture bottles with carbon power. Method: 147 venous blood cultures containing carbon powder were used to assess the microbial and antibiotic resistance detection ability of the FilmArray panel. Outcomes were compared with results of the clinical combination method and their consistency was analyzed. Results: FilmArray detected single microorganism in 121 samples, multiple microorganism in 9 cases and the consistency rate between the two methods was 90.6%. Among the 150 microorganisms detected, 85.1% (40/47) of staphylococcus contained the antibiotic resistant mecA gene, 15.3% (9/59) of Enterobacter detected the KPC gene, 7.7% (1/13) of Enterococcus has the vanA gene and the consistency with their clinical drug-resistant phenotypes were 93.6%, 86.4% and 100%, respectively. Conclusion: The identification rate of the FilmArray BCID panel using venous blood cultures with activated carbon powder was highly consistent with the outcomes of previous researchers using non-carbon powder blood culture bottles. It is capable of providing rapid and reliable results in the detection of pathogens present in automated blood culture systems.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Evaluation of the Performance of Filmarray Blood Culture Identification Panel on Detecting Blood Cultures Containing Activated Carbon Powder

Chen

Wang

2021

Preprint

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“…The leader must be an instructor with enough knowledge about the clinical setting and related technical details, the ability to motivate and support the team, understand processes, etc. [8].…”

Section: Multidisciplinary Change Phlebotomy Teammentioning

confidence: 99%

“…Moreover, surveillance and feedback when combined with education is more effective than education alone. Halstead et al [10] reported that although different intervention options are necessary to reduce BC contamination rate, a successful program is achieved by continuous education and feedback [8]. The education course follow by feedback conducted by Thong et al, led to reduce the rate of BCs contamination from 7% to less than 3% after the education [11].…”

Section: Education Of Phlebotomy Teammentioning

confidence: 99%

Update Review to Reduce Blood Culture Contamination

Hemati

bastaminejad

Maleki

2022

Egyptian Journal of Veterinary Sciences

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T HE incidence and mortality rate of sepsis is increasing worldwide. Rapid and accurate detection of bacteremia and fungemia is essential to improve the patient's condition. Health care providers, nurses, and possibly many laboratory staff are usually not well trained in proper blood culture techniques.The present guideline addresses the clinical importance of blood culture, its applications, and the correct technique for detecting pathogenic microorganisms that cause sepsis, and attempts to explain the place of blood culture in the management of sepsis and the appropriate method for obtaining a blood sample for culture. Describe false positives to reduce.Detection of bacteremia or fungi by blood culture is very important and vital in the management of patients with infection and can lead to the selection of appropriate antibiotics. Blood cultures (BCs) are important routine tests that are conducted in the clinical microbiology laboratory. Unfortunately, the common rate of BCs contamination is high which led to many clinical and economic consequences. The phlebotomy teams of blood sampling are very important to effectively reduce BCs contamination rate. Therefore, we conducted the current study to update our knowledge about the phlebotomy performances.

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“…BCs have long been recognized as one of the critically important and potentially life-saving diagnostic tests performed in clinical microbiology laboratories. [ 1 2 ] Sample collection for BC is a technically demanding procedure. Strict asepsis is followed during collection to prevent the growth of skin commensals/colonizers or environmental contaminants, which may overgrow and hence mask the actual pathogens in the blood if present, thus delaying or preventing the diagnosis of true bacteremia.…”

Section: Introductionmentioning

confidence: 99%

Effectiveness of Multimodal Intervention to Improve Blood Culture Collection in the Emergency Department

Sastry

Shaji

Madigubba

et al. 2022

Journal of Global Infectious Diseases

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Introduction: The blood culture (BC) contamination was a significant problem in our hospital, especially in the emergency department (ED). The study, therefore, was undertaken to improve the BC collection in the ED. Methods: The study was conducted for 1 year divided into two phases of 6 months each: Preintervention phase and intervention phase (regular and phlebotomist groups). The interventions comprised implementing standard protocol for BC collection and conducting educational sessions. In preintervention and regular groups, the BCs were collected by interns and technicians, while dedicated phlebotomist did so in the phlebotomist group. Data were analyzed and interpreted for the contamination rate as well as compliance in adequate filling of the requisition form. Statistical Package for the Social Sciences (SPSS) version 22. A value of P < 0.005 was considered statistically significant, and P < 0.01 was considered statistically significant. Results: In the preintervention group, 13.7% of specimens were reported as contaminated which was reduced to 4.2% and 3.2% in the regular and phlebotomist group, respectively, after intervention. Compliance of health-care workers to various elements of BC collection protocol was also found to be significantly improved in the intervention phase compared to the preintervention phase ( P < 0.001). Conclusions: Implementation of this multimodal intervention resulted in a drastic reduction in BC contamination and improvement in compliance to BC collection protocol and filling of various parameters in the BC requisition form, thus improving the overall effectiveness of BC testing. It was also noted that the contamination rate was further reduced by implementing dedicated phlebotomist.

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Reducing Blood Culture Contamination Rates: Experiences of Four Hospital Systems

Cited by 17 publications

References 32 publications

Evaluation of the Performance of Filmarray Blood Culture Identification Panel on Detecting Blood Cultures Containing Activated Carbon Powder

Evaluation of the Performance of Filmarray Blood Culture Identification Panel on Detecting Blood Cultures Containing Activated Carbon Powder

Update Review to Reduce Blood Culture Contamination

Effectiveness of Multimodal Intervention to Improve Blood Culture Collection in the Emergency Department

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