Abstract:BackgroundDermovate cream containing 0.05% clobetasol propionate is a very potent topical corticosteroid (TCS) used in the treatment of severe inflammatory dermatoses. Regular emollient therapy should continue alongside clobetasol propionate treatment, however, the impact on drug delivery to the skin when both products are applied at similar times is unknown.ObjectivesTo assess whether application of emollients at similar times to Dermovate cream alter the delivery of clobetasol propionate to the skin.MethodsT… Show more
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