Reduced phagocytic activity of human alveolar macrophages infected with Mycobacterium avium complex

Ikegami, Hiroaki; Yamasaki, Kei; Ogawa, Midori; Nemoto, Keiichi; Akata, Kentaro; Noguchi, Shingo; Fukuda, Kazumasa; Kawanami, Toshinori; Mukae, Hiroshi; Yatera, Kazuhiro

doi:10.1016/j.jiac.2022.07.018

Cited by 2 publications

(1 citation statement)

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“…When a virus invades, the body's immune response system is mobilized and multiple cells work together to fight it. One of the first lines of defense is the macrophage (Ikegami et al, 2022). AQP70‐3, a polysaccharide contained in the dried Akebia fruit, was reported to have immunomodulatory effects (Wang et al, 2021), and this finding was confirmed in macrophage and zebrafish models: the phagocytic activity of macrophages improved with increasing AQP70‐3 concentrations.…”

Section: Bioactivities Of Akebia Fruitmentioning

confidence: 99%

Akebia fruit: A review on its extraction, phytochemicals, bioactivities and applications

Li,

Yang,

Jin

et al. 2024

eFood

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Akebia fruit is a plant used for both medicinal and edible purposes. In recent years, due to the rich phytochemical composition with bioactive effects, Akebia fruit has attracted increasing attention on its composition analysis, active ingredients identification, and product applications. For example, the protein, sugar, amino acids, and vitamin C content of the pulp is higher than that of ordinary fruit. The seeds are not only processed into edible oil, it is also rich in protein and have the potential to be developed into a new resource with beneficial effects on human health. However, the research on the understanding of Akebia as a plant fruit is relatively lacking. In this review, an overview of Akebia fruit from food perspectives, including extraction methods and phytochemicals, bioactive functions, and various applications, were summarized. Finally, based on the current status and existing challenges, the prospect and future development direction of Akebia fruit were discussed.

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Section: Bioactivities Of Akebia Fruitmentioning

confidence: 99%