1988
DOI: 10.1002/art.1780310504
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Reduced mandibular dimensions and asymmetry in juvenile rheumatoid arthritis

Abstract: The pathogenesis of reduced mandibular dimensions and asymmetry was studied in 103 patients with juvenile rheumatoid arthritis. Abnormalities of the temporomandibular joint were intimately related to mandibular growth disturbances. Unilateral joint abnormality resulted in jaw asymmetry and underdevelopment on the affected side. Duration of disease and of corticosteroid therapy, age at disease onset, and age when the data were recorded were correlated with the size of the mandible. Our findings did not support … Show more

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Cited by 83 publications
(64 citation statements)
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“…2 The arthritis might lead to severe destruction of the cartilage and underlying bone, which can result in a deviating growth of the face. [3][4][5][6][7][8][9] To reduce these growth disturbances by early interventions, it is recommended that children with JIA be referred to a dentist for follow-up of facial growth and condylar destruction, especially as clinical and radiologic signs of inflammation are not always present, even though growth disturbances can be seen radiographically. 6 On the radiographs taken to evaluate facial growth, at least four vertebrae of the upper part of the cervical spine are usually visible.…”
Section: Introductionmentioning
confidence: 99%
“…2 The arthritis might lead to severe destruction of the cartilage and underlying bone, which can result in a deviating growth of the face. [3][4][5][6][7][8][9] To reduce these growth disturbances by early interventions, it is recommended that children with JIA be referred to a dentist for follow-up of facial growth and condylar destruction, especially as clinical and radiologic signs of inflammation are not always present, even though growth disturbances can be seen radiographically. 6 On the radiographs taken to evaluate facial growth, at least four vertebrae of the upper part of the cervical spine are usually visible.…”
Section: Introductionmentioning
confidence: 99%
“…Arthritis of the TMJ in the growing, young individual can have significant implications for craniomandibular growth and development 3,4,5 . This is because the mandibular condylar cartilage serves as the basis of the primary mandibular endochondral growth site since the growth site is placed within the intracapsular joint.…”
mentioning
confidence: 99%
“…A artrite na ATM, com acometimento do côndilo no período de desenvolvimento é o mais importante fator que inibe o crescimento da mandíbula e conseqüente crescimento facial nestes pacientes 3,4,55,60,61,62,63,64 . Outros fatores foram estudados tentando estabelecer suas relações com as alterações de crescimento.…”
Section: Crescimento Facial Em Pacientes Com Aijunclassified
“…O uso prolongado de corticosteróides, acima de três meses, parece influenciar o tamanho mandibular 3,55 , por sua ação prejudicial ao crescimento, e também por reduzir a densidade de estruturas ósseas da ATM, facilitando deformidades 60 , porém esta relação não foi observada em outros estudos 5,65,66 , considerando que a utilização prolongada de corticosteróides reflete apenas maior gravidade da doença e não necessariamente um papel patogênico específico destas drogas na ATM 5 . A influência do comprometimento cervical no crescimento facial é outro fator estudado, sendo descrito que afecções cervicais são mais freqüentes em pacientes com alterações de ATM 65 , sendo que as alterações na postura da cabeça podem causar alterações na posição da mandíbula durante o crescimento, sem interferir com o tamanho mandibular 3 . O prejuízo da função mandibular por dor ou por diminuição do tônus muscular também é apontado como possível fator causal nas alterações de crescimento facial em crianças com AIJ 55,59,67,68 , por diminuir a estimulação funcional do crescimento condilar e mandibular 64 .…”
Section: Crescimento Facial Em Pacientes Com Aijunclassified
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