2019
DOI: 10.1007/s00339-019-3237-x
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Reduced graphene oxide/silver nanohybrid as a multifunctional material for antibacterial, anticancer, and SERS applications

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Cited by 39 publications
(15 citation statements)
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“…28 Furthermore, RGO-based metal oxide nanocomposites have garnered much attention as antimicrobials in the last few years. [29][30][31][32] Therefore, this study aims to synthesize and characterize the RGO-AgO, RGO-ZnO and RGO-NiO nanocomposites, in addition to evaluate their antimicrobial and antibiolm activities and the effect of UV illumination, as well as to determine the exact antimicrobial reaction mechanism. The synthesized nanocomposites may nd potential applications in industries and medical surgeries as effective materials to eliminate or reduce the dangerous and fetal effects produced by the pathogenic microbes.…”
Section: Introductionmentioning
confidence: 99%
“…28 Furthermore, RGO-based metal oxide nanocomposites have garnered much attention as antimicrobials in the last few years. [29][30][31][32] Therefore, this study aims to synthesize and characterize the RGO-AgO, RGO-ZnO and RGO-NiO nanocomposites, in addition to evaluate their antimicrobial and antibiolm activities and the effect of UV illumination, as well as to determine the exact antimicrobial reaction mechanism. The synthesized nanocomposites may nd potential applications in industries and medical surgeries as effective materials to eliminate or reduce the dangerous and fetal effects produced by the pathogenic microbes.…”
Section: Introductionmentioning
confidence: 99%
“…Moreover, the Ag + ions, AgNPs, GO and rGO can stimulate the generation of reactive oxygen species (ROS), which results in oxidative stress on the membrane with consequent bacterial cell death. 42,43 The BG-AgrGO/PCL composite coating exhibits a relatively lower antibacterial performance when compared to the AgBG-GO/PCL composite coating. This is due to the slow release of Ag + ions in the AgrGO nanocomposite that persist in a stable structure for a fairly long duration of time to produce ROS for bacterial inactivation.…”
Section: Antimicrobial Activity Of Agbg/pcl Agbg-go/pcl Agbg-rgo/pcl ...mentioning
confidence: 99%
“…As previously reported, the cytotoxic effects of rGO nanocomposites were evaluated using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) and neutral red uptake (NRU) assays. [52,53] Briefly, 2 Í 10 3 HaCaT cells per well were seeded in 96-well cell culture plates and exposed to TM@rGO or rGO for 24 h. After washing with phosphatebuffered saline (PBS, Gibco, USA) and exposure to rGO nanocomposites, an MTT solution (Sigma-Aldrich, USA) was added to each well at a final concentration of 0.5 mg mL −1 and the cells were incubated for 1 h. The formazan crystals formed during the process were dissolved in 50% dimethyl sulfoxide (DMSO) (Sigma-Aldrich, USA) and 50% methanol (Merck, USA). For the NRU assays, NP-exposed cells were washed twice with PBS and incubated for 3 h in OPTI-MEMI (Gibco, USA), which contained 40 ng mL −1 of neutral red reagent (Sigma-Aldrich, USA).…”
Section: Introduction Of Tm@rgo Intomentioning
confidence: 99%