“…Preference DE genes in this subnetwork include gria3 , a member of the AMPA glutamate receptor family known to be an important component of the female preference response50. Also scn2a and scn8a , which are known to have molecular functions in brain circuits that mediate specific behaviors51, agap3 , involved in signal transduction, syn1 , known to be involved in synaptic plasticity and social behavior52, baz2a , which regulates transcription of androgen receptors, and slc24a2 , a critical gene in signal transduction53 with known roles in cognition and memory54, and a target of the immediate early gene fosl1 . The network structure reveals these genes are connected to other known components of the female preference transcriptional response3,18, including neuroligin-2, neuroligin-3, stmn2a & stmn2b .…”