Reduced baroreflex sensitivity in acute alcohol withdrawal syndrome and in abstained alcoholics

Autonomy of Autonomic Dysfunction in Major Depression

“…Of these, especially compression entropy Hc has been shown to be a very sensitive parameter of autonomic modulation (12,13) in various psychiatric diseases. Applying this parameter, a better discrimination between groups was achieved in contrast to established linear time and frequency domain measures, such as RMSSD or LF/HF ratio.…”

“…A detailed description has been published previously (13,29). Spontaneous sequences of at least three consecutive beats were analyzed, when an increased systolic blood pressure (SBP) of at least 1 mm Hg caused an increased BBI of at least 5 ms (bradycardic sequence) or a decreased SBP caused a decreased beat-tobeat interval (tachycardic sequence).…”

“…To assess heart rate and blood pressure dynamics in a more complex way, an analysis based on joint symbolic dynamics was applied (36), which has been described previously (13). Here, the beat-to-beat changes of RR and SBP are each coarse-grained to two different symbols: increasing values are coded as "1," whereas decreasing and unchanged values are coded as "0," respectively.…”

“…Furthermore, methodinherent limitations, such as the widely used application of linear algorithms for RR interval processing, might prevent the detection of significant group effects. In this respect, the application of novel nonlinear techniques has largely improved the detection of autonomic dysfunction, either in depression (10,11) as well as in other psychiatric disorders (12,13).…”

Mortalidad en el síndrome de abstinencia alcohólica

“…(2006) han demostrado una intensa disminución de la sensibilidad del reflejo de los barorreceptores en relación con la situación hiperadrenérgica propia del síndrome de abstinencia y que persiste, aunque atenuada, pasado el episodio. La relación entre esta alteración y el aumento de la mortalidad es inespecífica y se ha descrito en pacientes sin SAA (15). Otra posible causa de arritmias ventriculares graves es la prolongación del intervalo QT.…”