Redox Imaging of Inflammation in Asthma

Ratanamaneechat, Suphagaphan; Neumann, Donald R.; DiFilippo, Frank P.; Comhair, Suzy; Asosingh, Kewal; Ghosh, Sudakshina; Grandon, Deepa; Khan, Arif; Aronica, Mark A.; Erzurum, Serpil C.

doi:10.1164/rccm.201310-1872le

Cited by 8 publications

(2 citation statements)

References 22 publications

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“…Another study reported greater tracer uptake in the lower lobes, suggesting that inflammation in asthma subjects demonstrated a gradient with lobar predominance. This finding was subsequently confirmed with the assessment of inflammatory cells in the upper and lower lobe bronchoalveolar lavage [194]. Another promising and exciting use of SPECT has recently been described by Farahi et al [195].…”

Section: Single-photon Emission Tomographymentioning

confidence: 70%

Novel imaging approaches in adult asthma and their clinical potential

Hartley

Baldi

Brightling

et al. 2015

Expert Review of Clinical Immunology

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Currently, imaging in asthma is confined to chest radiography and CT. The emergence of new imaging techniques and tremendous improvement of existing imaging methods, primarily due to technological advancement, has completely changed its research and clinical prospects. In research, imaging in asthma is now being employed to provide quantitative assessment of morphology, function and pathogenic processes at the molecular level. The unique ability of imaging for non-invasive, repeated, quantitative, and in vivo assessment of structure and function in asthma could lead to identification of 'imaging biomarkers' with potential as outcome measures in future clinical trials. Emerging imaging techniques and their utility in the research and clinical setting is discussed in this review.

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Section: Single-photon Emission Tomographymentioning

confidence: 70%

Novel imaging approaches in adult asthma and their clinical potential

Hartley

Baldi

Brightling

et al. 2015

Expert Review of Clinical Immunology

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show abstract

“…Single-photon emission CT images might also be able to quantify different types of inflammation in patients with asthma and other lung diseases. 58 These modalities, although prevalent in many centers, have not been extensively studied in asthmatic patients to determine their applicability as clinical biomarkers.…”

Section: Novel Ct Applicationsmentioning

confidence: 99%

Clinical potential for imaging in patients with asthma and other lung disorders

DeBoer

Spielberg

Brody

2017

Journal of Allergy and Clinical Immunology

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The ability of lung imaging to phenotype patients, determine prognosis, and predict response to treatment is expanding in clinical and translational research. The purpose of this perspective is to describe current imaging modalities that might be useful clinical tools in patients with asthma and other lung disorders and to explore some of the new developments in imaging modalities of the lung. These imaging modalities include chest radiography, computed tomography, lung magnetic resonance imaging, electrical impedance tomography, bronchoscopy, and others.

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Imaging in Asthma

Gulhane¹,

Chen²

2021

Molecular Imaging

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Redox Imaging of Inflammation in Asthma

Cited by 8 publications

References 22 publications

Novel imaging approaches in adult asthma and their clinical potential

Novel imaging approaches in adult asthma and their clinical potential

Clinical potential for imaging in patients with asthma and other lung disorders

Imaging in Asthma

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