Redefining Hypertension — Assessing the New Blood-Pressure Guidelines

Impact of cumulative SBP and serious adverse events on efficacy of intensive blood pressure treatment

“…New guidelines for management of BP, redefine the therapeutic target as BP less than 130/80 mmHg [31,32]. For primary prevention, the guidelines recommend pharmacology treatment among individuals with BP more than 130/80 mmHg and cardiovascular risk more than 10% or those with cardiovascular risk less than 10% but BP more than 140/90 mmHg.…”

Blood pressure targets for hypertension in patients with type 2 diabetes

“…Although orthostatic hypotension is associated with poor patient outcomes, the evidence regarding the risk of this complication after intensive or standard blood pressure control is insufficient (3,48,49). Primary studies and meta-analyses did not discuss the importance of pulse pressure in reducing morbidity and mortality in adults with diabetes (50).…”

“…We have no evidence, we are unable to estimate an effect, or we have no confidence in the estimate of effect for this outcome. No evidence is available or the body of evidence has unacceptable deficiencies, precluding reaching a conclusion (175)(176)(177)(178)(179)(180)(181)(182)(183)(184)(185)(186)(187)(188)(189)(190), 2010-2014 (191)(192)(193)(194)(195)(196)(197)(198)(199)(200)(201)(202)(203)(204)(205)(206)(207); publications of reviews (3)(4)(5)30,31,(33)(34)(35)(36)(37)(38)40,50,90,93,208,209); publications of gu...…”

Nutritional Genomics of Cardiovascular Disease

“…It has been reported that, for individuals between the ages of 40–69 years, every 20 mmHg increase in systolic blood pressure and 10 mmHg increased in diastolic blood pressure doubles the risk for CVD (44,45). Weight loss, increased physical activity and a healthy diet with decreased salt intake are some of the lifestyle modifications advocated for management of hypertension.…”