Red pepper Capsicum baccatum: source of antiadhesive and antibiofilm compounds against nosocomial bacteria

Borowski, Rafael Gomes Von; Zimmer, Karine Rigon; Leonardi, Bianca Franco; Trentin, Danielle da Silva; Campos-Silva, Rodrigo; Barros, Muriel Primon de; Macêdo, Alexandre José; Gnoatto, Simone Cristina Baggio; Gosmann, Grace

doi:10.1016/j.indcrop.2018.10.011

Cited by 29 publications

(20 citation statements)

References 54 publications

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“…50,57 In this context, some studies have suggested that plant-derived peptide fractions exhibit antiadhesive properties. 43,[58][59][60] Recent literature reviews have shown that peptides and peptidomimetics from different sources have been investigated for their prominent antibiofilm activity. [61][62][63][64][65] There are no previous studies demonstrating a relationship between 2S sulfur-rich seed storage (2SS) proteins or peptides and antibiofilm activity.…”

Section: Discussionmentioning

confidence: 99%

“…A voucher specimen (ICN 181469) was identified and deposited at the Herbarium of Universidade Federal of Rio Grande (UFRGS, Brazil). The seeds and extracts were obtained and prepared according to Gomes Von Borowski et al 43 The most active extract was lyophilized to obtain the residual aqueous extract from seeds (RAqS).…”

Section: Plant Materials and Extractionmentioning

confidence: 99%

“…Previously, we obtained a protein extract from C. baccatum seeds (RAqS) with potential antibiofilm activity. 43 Herein, further purification steps were performed in order to obtain the bioactive fraction from RAqS responsible for antibiofilm activity. After chromatographic collection of 14 fractions, the ninth fraction was determined to be the one containing the biological activity (Figure S2).…”

Section: Bioguided Fractionation and Identification Of Antibiofilm Peptides From C Baccatummentioning

confidence: 99%

“…[35][36][37][38][39][40][41][42] Recently, we demonstrated that an aqueous extract of C. baccatum seeds decreased S. epidermidis biofilm formation by 80%, indicating that this red pepper is a potential source of antibiofilm and antiadhesive compounds. 43 In the present study, we purified and identified antibiofilm and antiadhesive peptides from C. baccatum using chromatography-tandem mass spectrometry, MALDI-MS/MS and bioinformatics tools. We demonstrated the ability of Capsicum storage peptides (CSP) to prevent biofilm formation by methicillin-resistant S. epidermidis without antibiotic mechanisms.…”

Section: Introductionmentioning

confidence: 99%

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Red pepper peptide coatings control Staphylococcus epidermidis adhesion and biofilm formation

Borowski

Barros

Silva

et al. 2020

International Journal of Pharmaceutics

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HAL is a multi-disciplinary open access archive for the deposit and dissemination of scientific research documents, whether they are published or not. The documents may come from teaching and research institutions in France or abroad, or from public or private research centers. L'archive ouverte pluridisciplinaire HAL, est destinée au dépôt et à la diffusion de documents scientifiques de niveau recherche, publiés ou non, émanant des établissements d'enseignement et de recherche français ou étrangers, des laboratoires publics ou privés.

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Section: Discussionmentioning

confidence: 99%

Section: Plant Materials and Extractionmentioning

confidence: 99%

Section: Bioguided Fractionation and Identification Of Antibiofilm Peptides From C Baccatummentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Red pepper peptide coatings control Staphylococcus epidermidis adhesion and biofilm formation

Borowski

Barros

Silva

et al. 2020

International Journal of Pharmaceutics

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“…A typical South-American pepper (Capsicum baccatum) is the most consumed in Brazil and highly relevant in regional gastronomy as flavouring and colourant agent. Besides antioxidant properties, C. baccatum extracts display anti-inflammatory activities, may combat antibiotic-resistant bacteria, prevent bacterial adhesion and biofilm formation (von Borowski et al, 2019).…”

Section: Introductionmentioning

confidence: 99%

Flour from 'fruits and vegetables' waste with addition of a South‐American pepper (Capsicum baccatum) proposed as food ingredient

Mendes

Favre

Rolandelli

et al. 2019

Int J of Food Sci Tech

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Summary The objective of this work was to evaluate the physicochemical properties of previously characterised flours obtained by milling the solid waste from the manufacture of an isotonic drink produced with various fruits and vegetables (FVR) to which powdered pepper fruits (PF) were added. Aqueous extracts were also prepared and encapsulated for protecting their functional compounds and improving their solubility. The encapsulation yields of the spray‐drying processes were 90% and 64% for PF and FVR‐PF, respectively. The addition of PF to FVR improved antioxidant capacity, stability and appearance, providing reddish colour. FT‐IR spectra reflected the addition of PF by changes in the absorbances at wave numbers typical of carotenoids, acylglycerols, chlorophylls and those related to antioxidant capacity. The encapsulated extracts could be applied when solubility is needed in hydrophilic media. The obtained flours with PF addition are suitably cheap, stable functional food ingredients for industrial uses, such as breading or seasoning ingredients.

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Early biofilm and streamer formation is mediated by wall shear stress and surface wettability: A multifactorial microfluidic study

et al. 2022

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Biofilms are intricate communities of microorganisms encapsulated within a selfproduced matrix of extra-polymeric substances (EPS), creating complex threedimensional structures allowing for liquid and nutrient transport through them.These aggregations offer constituent microorganisms enhanced protection from environmental stimuli-like fluid flow-and are also associated with higher resistance to antimicrobial compounds, providing a persistent cause of concern in numerous sectors like the marine (biofouling and aquaculture), medical (infections and antimicrobial resistance), dentistry (plaque on teeth), food safety, as well as causing energy loss and corrosion. Recent studies have demonstrated that biofilms interact with microplastics, often influencing their pathway to higher trophic levels. Previous research has shown that initial bacterial attachment is affected by surface properties.Using a microfluidic flow cell, we have investigated the relationship between both wall shear stress (τ w ) and surface properties (surface wettability) upon biofilm formation of two species (Cobetia marina and Pseudomonas aeruginosa). We investigated biofilm development on low-density polyethylene (LDPE) membranes, Permanox ® slides, and glass slides, using nucleic acid staining and end-point confocal laser scanning microscopy. The results show that flow conditions affect biomass, maximum thickness, and surface area of biofilms, with higher τ w (5.6 Pa) resulting in thinner biofilms than lower τ w (0.2 Pa). In addition, we observed differences in biofilm development across the surfaces tested, with LDPE typically demonstrating more overall biofilm in comparison to Permanox ® and glass. Moreover, we demonstrate the formation of biofilm streamers under laminar flow conditions within straight micro-channels.

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Red pepper Capsicum baccatum: source of antiadhesive and antibiofilm compounds against nosocomial bacteria

Cited by 29 publications

References 54 publications

Red pepper peptide coatings control Staphylococcus epidermidis adhesion and biofilm formation

Red pepper peptide coatings control Staphylococcus epidermidis adhesion and biofilm formation

Flour from 'fruits and vegetables' waste with addition of a South‐American pepper (Capsicum baccatum) proposed as food ingredient

Early biofilm and streamer formation is mediated by wall shear stress and surface wettability: A multifactorial microfluidic study

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