Red cell polymorphisms in nonhuman primates: A review

Socha, W. W.; Blancher, Antoine; Moor‐Jankowski, J.

doi:10.1111/j.1600-0684.1995.tb00182.x

Cited by 26 publications

(12 citation statements)

References 83 publications

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“…Erythrocyte typing for Le a or Le b by direct hemagglutination, as done for humans (22) was not useful; 12 of 13 animals tested (including animals A and D) were negative for both determinants. These results agree with findings in M. mulatta (W. Socha, personal communication), indicating that direct hemagglutination does not allow detection of rhesus monkey erythrocyte Le antigens or ABO-blood group antigens (55). We then tested for Le a or Le b antigens in saliva and gastric juice by a hemagglutination inhibition method (45).…”

Section: Lewis Determination In Host Secretionssupporting

confidence: 80%

Host Lewis phenotype‐dependentHelicobacter pyloriLewis antigen expression in rhesus monkeys

et al. 2006

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Both human and H. pylori populations are polymorphic for the expression of Lewis antigens. Using an experimental H. pylori challenge of rhesus monkeys of differing Lewis phenotypes, we aimed to determine whether H. pylori populations adapt their Lewis phenotypes to those of their hosts. After inoculation of four monkeys with a mixture of seven strains identified by RAPD-polymerase chain reaction, H. pylori Lewis expression was followed in 86 isolates obtained over 40 wk. Host Lewis(a/b) secretion status was characterized by immunological assays. Fingerprints of the predominating strain (J166) were identical in all four animals after 40 wk, but its Lewis phenotype had substantial variability in individual hosts. At 40 wk, J166 populations from two Lewis(a-b+) animals predominantly expressed Lewis(y). In contrast, J166 populations had switched to a Lewis(x) dominant phenotype in the two Lewis(a+b-) animals; a frame shift in futC, regulating conversion of Lewis(x) to Lewis(y), accounted for the phenotypic switch. The results indicate that individual cells in H. pylori populations can change Lewis phenotypes during long-term colonization of natural hosts to resemble those of their hosts, providing evidence for host selection for bacterial phenotypes.

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Section: Lewis Determination In Host Secretionssupporting

confidence: 80%

Host Lewis phenotype‐dependentHelicobacter pyloriLewis antigen expression in rhesus monkeys

et al. 2006

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“…Initial experiments confirmed that RBC ABO epitopes were not present in sufficient quantity to be detected by forward grouping 13 . Instead, the presence of antibodies to A and B antigens in both the donor and the recipient monkey established a common type O blood group (data not shown).…”

Section: Resultsmentioning

confidence: 91%

“…Blood group compatibility was determined with reverse typing 12,13 . Serum samples from the donor and eligible recipients were tested for antibodies to A and B antigens with standardized human red blood cells (RBC) reagents (Dominion Biologicals Ltd, Dartmouth, Nova Scotia, Canada).…”

Section: Methodsmentioning

confidence: 99%

Characterization of blood‐borne transmission of simian foamy virus

et al. 2006

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“…For example, studies on blood group polymorphisms indicate that bonobos ( N < 10) are virtually monomorphic for four major blood groups compared with considerable variation in chimpanzees ( Moor‐Jankowski et al . 1972, 1975 ; Socha et al . 1995 ).…”

Section: Discussionmentioning

confidence: 99%

Patterns of microsatellite polymorphism in the range‐restricted bonobo (Pan paniscus): considerations for interspecific comparison with chimpanzees (P. troglodytes)

et al. 2000

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The endangered great ape, Pan paniscus (bonobo) has the smallest range of the African apes. Virtually nothing is known about the genetic diversity or genetic structure of this species, while substantial amounts of polymorphism have been reported for the bonobo's widespread congener, the chimpanzee (P. troglodytes). Given its restricted range, what is the extent of genetic variation in the bonobo relative to the chimpanzee, and is the bonobo genetically depauperate? To investigate patterns of genetic polymorphism, bonobos of wild origin were genotyped for 28 microsatellite loci. The mean number of alleles per locus (5.2) and the mean observed heterozygosity (0.52) in bonobos were similar to variation observed in a wild chimpanzee community (P. t. schweinfurthii). The rarer bonobo is not genetically depauperate and may have genetic diversity comparable to the eastern chimpanzee subspecies. Bonobos have approximately 55% of the allelic diversity and 66% of the observed heterozygosity exhibited by all three chimpanzee subspecies sampled across equatorial Africa. Resampling techniques were used to quantify the effects of sample size differences and number and choice of loci between bonobos and chimpanzees. The examination of these variables underscores their importance in accurately interpreting interspecific comparisons of diversity estimates.

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Red cell polymorphisms in nonhuman primates: A review

Cited by 26 publications

References 83 publications

Host Lewis phenotype‐dependentHelicobacter pyloriLewis antigen expression in rhesus monkeys

Host Lewis phenotype‐dependentHelicobacter pyloriLewis antigen expression in rhesus monkeys

Characterization of blood‐borne transmission of simian foamy virus

Patterns of microsatellite polymorphism in the range‐restricted bonobo (Pan paniscus): considerations for interspecific comparison with chimpanzees (P. troglodytes)

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