Red Cell Banking and the Production
of a Factor VIII Concentrate

Cumming, R.A.; Davies, S.H.; Ellis, D.; Grant, W.

doi:10.1159/000465058

Cited by 2 publications

(2 citation statements)

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“…After a period of study in Cohn’s laboratory at Harvard University, Dr Ellis designed and installed equipment to produce normal immunoglobulin for the prevention and treatment of measles; produced from 1952, it was Scotland’s first plasma product (Figure 1). Further products were developed 5 (Figure 2) including a factor VIII concentrate 6 and a fibrinogen concentrate in 1956, and human albumin and anti-vaccinia immunoglobulin in 1965.

Figure 1.Normal Immunoglobulin, 1950’s (© Antonia Reeve).

Figure 2.Early freeze dried Products (a) Plasma, (b) Albumin, (c) Fibrinogen, (d) Factor VIII (AHF) Concentrate (© Antonia Reeve). …”

Section: –1974mentioning

confidence: 99%

The manufacture of blood plasma products in Scotland: a brief history

Foster¹

2016

Scott Med J

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A number of essential clinical products are derived from human blood plasma, including immunoglobulin products for the treatment of infections and disorders of immunity; albumin for protein and fluid replacement and coagulation factors for the treatment of haemophilia and other disorders of haemostasis. For many years, these protein pharmaceuticals were manufactured by the Scottish National Blood Transfusion Service (SNBTS) at its Scottish Protein Fractionation Centre (PFC) in Edinburgh, a contribution which ended with the closure of the PFC in 2008. The origins and development of plasma fractionation in Scotland are summarised in this article, as well as issues which contributed to the closure of the PFC.

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Figure 1.Normal Immunoglobulin, 1950’s (© Antonia Reeve).

Figure 2.Early freeze dried Products (a) Plasma, (b) Albumin, (c) Fibrinogen, (d) Factor VIII (AHF) Concentrate (© Antonia Reeve). …”

Section: –1974mentioning

confidence: 99%