Red blood cell transfusion, risks and limitations

Mercuriali, F.; Inghilleri, G.

doi:10.1007/978-3-7091-7658-0_10

Cited by 10 publications

(8 citation statements)

References 44 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In the tranexamic acid group, 2 patients had blood transfusions, as opposed to 7 in the placebo group (p = 0.1). 4 transfusions were given in the tranexamic group versus 25 transfusions in the placebo group, a reduction of 84% (p = 0.04).There are obvious medical as well as financial advantages in reducing transfusions to a minimum (Mercuriali andInghilleri 1999, Hadjianastassiou et al 2002). 1 blood transfusion costs 93 Euro; 4 ampoules (2 grams) of tranexamic acid cost 18 Euro.…”

Section: Discussionmentioning

confidence: 99%

Tranexamic acid reduces blood loss and blood transfusions in primary total hip arthroplastyA prospective randomized double-blind study in 40 patients

Blønd

Sonne‐Holm

Holm

et al. 2003

Acta Orthopaedica Scandinavica

138

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 99%

Tranexamic acid reduces blood loss and blood transfusions in primary total hip arthroplastyA prospective randomized double-blind study in 40 patients

Blønd

Sonne‐Holm

Holm

et al. 2003

Acta Orthopaedica Scandinavica

138

View full text Add to dashboard Cite

show abstract

“…The noninfectious complications are related to concomitant transfusions of leucocytes, such as fever, alloimmunization, refractoriness to platelet transfusion, acute lung injury, and immunossupression. 7,8 A retrospective study has shown that blood transfusion was related to a greater rate of hospital infection. 10 Other undesirable effects caused by the use of blood-derived substances are lung edema due to hypervolemia, hypothermia, coagulopathies, and toxicity due to citrate.…”

mentioning

confidence: 99%

Evaluation of Blood Transfusion Effects on Mixed Venous Oxygen Saturation and Lactate Levels in Patients With Sirs/Sepsis

Mazza¹,

Machado²,

Mazza³

et al. 2005

Clinics

View full text Add to dashboard Cite

Evaluation of blood transfusion effects on mixed venous oxygen saturation and lactate levels in patients with SIRS/sepsis. Clinics. 2005;60(4):311-6. PURPOSE: To evaluate the effects of red blood cell transfusion in patients with SIRS/sepsis who presented hemoglobin levels under 9.0 g/dL at intensive care unit admission, using two parameters of organ perfusion: mixed venous oxygen saturation and serum lactate levels. METHODS: All patients admitted to the intensive care unit with SIRS/sepsis, as defined by Consensus Conference in 1992, and hemoglobin levels under 9.0 g/dL were included. Hemoglobin levels, mixed venous oxygen saturation, and lactate levels were collected before red blood cell transfusion (pre-T) and up to 1 hour after transfusion (post-T). These variables were analyzed through a paired t test, and results were considered significant if P ≤ .05. RESULTS: Twenty-nine patients (17 male, 12 female) with ages of 61.9 ± 15.1 (mean ± SD) years (range, 21-85 years) and a mean APACHE II score of 12.5 ± 3.75 (7-21) were transfused with a mean of 1.41 packed red cell units. A significant increase in hemoglobin levels was reached by blood transfusion, from 8.

show abstract

“…In addition, the implementation of the AB programme resulted in a further decrease in the need for HB transfusion. This finding is especially relevant in an era in which the risk and cost of transfusion are of increasing importance [22]. Perhaps most importantly, the institution of MBL is associated with a decrease in morbidity and mortality rates in patients undergoing resection.…”

Section: Discussionmentioning

confidence: 99%