Abstract:Red blood cell transfusions are performed at all ages. Hemoglobin concentration and hematocrit rate are the primary data used to indicate these transfusions. The values of arterial serum lactate and SvO2were seldom used. Most patients transfused were submitted to some form of therapeutic procedure, and in many cases, transfusions were carried out in patients with multiple organ and system dysfunctions.
“…Transfundir con concentrado eritrocitario (CE) a neonatos críticamente enfermos con o sin anemia ha sido una conducta aceptada para incrementar el contenido arterial de oxígeno (CaO 2 ) y con ello mejorar la oxigenación tisular. Por lo anterior, se considera que el CaO 2 es un dato confiable y accesible para inferir la oxigenación tisular [1][2][3][4][5] La trasfusión de CE no está exenta de riesgos, tal como la modificación de la hemodinámica cardiovascular. A diferencia de la incorporación de volúmenes de líquidos, el aporte de CE mantiene un volumen intravascular por mayor tiempo, por lo que esta sobrecarga de volumen puede modificar la estabilidad hemodinámica del paciente.…”
Revista Mexicana de PEDIATRÍA www.medigraphic.org.mx Comparación del efecto de la transfusión de concentrado eritrocitario en el contenido arterial de oxígeno de neonatos sin sepsis, con sepsis y choque séptico
“…Transfundir con concentrado eritrocitario (CE) a neonatos críticamente enfermos con o sin anemia ha sido una conducta aceptada para incrementar el contenido arterial de oxígeno (CaO 2 ) y con ello mejorar la oxigenación tisular. Por lo anterior, se considera que el CaO 2 es un dato confiable y accesible para inferir la oxigenación tisular [1][2][3][4][5] La trasfusión de CE no está exenta de riesgos, tal como la modificación de la hemodinámica cardiovascular. A diferencia de la incorporación de volúmenes de líquidos, el aporte de CE mantiene un volumen intravascular por mayor tiempo, por lo que esta sobrecarga de volumen puede modificar la estabilidad hemodinámica del paciente.…”
Revista Mexicana de PEDIATRÍA www.medigraphic.org.mx Comparación del efecto de la transfusión de concentrado eritrocitario en el contenido arterial de oxígeno de neonatos sin sepsis, con sepsis y choque séptico
“…Anemia is a common problem in critically ill children admitted to pediatric intensive care units (PICU) due to the underlying causes and severity of the disease, malnutrition, and hemodilution [1]. Up to 50% of children who are admitted to PICU receive red blood cells (RBCs) transfusion [2].…”
Background: Transfusion of red blood cells (RBCs) is a common intervention in Pediatric Intensive Care Units (PICU) due to anemia occurring in over one-third of children hospitalized there. Objectives: To establish the relation between transfusion of RBCs and nosocomial infections in PICU and evaluate its impact on absolute lymphocytic count. Patients and methods: A case-control study carried out on 200 critically ill children admitted to PICU, of which one hundred received blood transfusion and one hundred did not. All patients underwent history taking and clinical examination. Results: A statistically significant higher prevalence of mechanical ventilation, central venous catheterization, PRISM score and longer PICU length of stay were observed in the transfused group compared with the non-transfused group (P < 0.001). Nosocomial infections were present in 62% patients in the transfused group and in 32% patients in the non-transfused group (P < 0.05), including nosocomial pneumonia, bacteremia, and urinary tract infection. Mechanical ventilation, presence of central venous catheter, number and age of transfused RBCs were risk predictors for nosocomial infections. Lymphopenia was evident in the transfused group. Conclusion: Nosocomial infections are related with red blood cells transfusion in patients hospitalized in PICU. Mechanical ventilation, presence of central venous catheter, number and age of transfused RBCs, and lymphopenia were risk predictors for nosocomial infections.
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