Red Blood Cell Distribution Width Predicts Myocardial Infarction and Mortality After Vascular Surgery–A Prospective Cohort Study

Albuquerque, Francisca Vieira da Silva Caldeira de; Dias-Neto, Marina; Rocha‐Neves, João; Reis, Pedro

doi:10.1007/s00268-022-06441-z

Cited by 1 publication

(1 citation statement)

References 37 publications

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“…RDW is a numerical measure of the size variability of circulating erythrocytes. Elevated RDW levels imply that the size distribution of red blood cells yields a greater variation than normal RDW values and signal bone marrow dysfunction induced by vitamin B12, folate, or iron deficiencies [10]. Pouladzadeh et al divided 331 patients with COVID-19 into 'severe' and 'non-severe' cohorts and evaluated their RDW-SD levels [11].…”

Section: Discussionmentioning

confidence: 99%

Evaluation of the Diagnostic Value of Hematologic Parameters and Ratios in SARS-CoV-2 VOC-202012/01 Mutant Population

Seyit¹,

Avcı²,

Yılmaz³

et al. 2022

Cureus

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In this study, we set out to study possible differences between individuals with and without VOC 202012/01 variant by using less costly complete blood count analytes and quickly analyzing the samples and ratios derived from these analytes. For this purpose, we assessed neutrophil, lymphocyte, platelet, and Red Blood Cell Distribution Width-Standard Deviation (RDW-SD) levels among complete blood count parameters (CBC) (identification and count of red blood cell, neutrophil, eosinophil, basophil, lymphocyte, monocyte, platelet) as well as the neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR). MethodsA retrospective cross-sectional study was performed over the course of two months (from May to June 2021) on 212 patients who presented to the emergency department of a tertiary hospital with Covid-19 symptoms and took SARS-CoV2 PCR and CBC tests. The polymerase chain reaction (PCR)-confirmed SARS-CoV2 positive patients and their hospitalization data were gathered from the public health management system. Their VOC-202012/01 mutation status was also confirmed by this system. ResultsRDW-SD, RDW, NLR, and PLR indexes, as well as C-reactive protein (CRP), and lactate dehydrogenase (LDH) values, were higher in the patients with VOC-202012/01 mutation (p<0.0001) than those without mutation, while hemoglobin and hematocrit counts and ratio, as well as eosinophil and lymphocyte counts, remained lower in the patients with mutation (p<0.0001). ConclusionNLR and RLP ratios derived from hematological parameters and models based on these ratios and RDW-SD are cheaper and more widely used. Our study suggests that the hematological analytes, the ratios obtained from these analytes, and the models created through these ratios in patients presenting to the ED with COVID-19-like symptoms and having positive reverse transcription polymerase chain reaction (RT-PCR) test results were significantly different in those with and without the VOC-202012/01 mutation. The bottom line is that they can serve as reliable predictors in the assessment of patients with the VOC-202012/01 mutation.

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Section: Discussionmentioning

confidence: 99%

Evaluation of the Diagnostic Value of Hematologic Parameters and Ratios in SARS-CoV-2 VOC-202012/01 Mutant Population

Seyit¹,

Avcı²,

Yılmaz³

et al. 2022

Cureus

View full text Add to dashboard Cite

show abstract

Red Blood Cell Distribution Width Predicts Myocardial Infarction and Mortality After Vascular Surgery–A Prospective Cohort Study

Abstract: Red blood cell distribution width predicts myocardial infarction and mortality after vascular surgery -A prospective cohort studyA amplitude de distribuição dos glóbulos rubros prediz a ocorrência de enfarte do miocárdio e morte após cirurgia vascular -Estudo coorte prospetivo Abril,

Cited by 1 publication

References 37 publications

Evaluation of the Diagnostic Value of Hematologic Parameters and Ratios in SARS-CoV-2 VOC-202012/01 Mutant Population

Evaluation of the Diagnostic Value of Hematologic Parameters and Ratios in SARS-CoV-2 VOC-202012/01 Mutant Population

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