Red and/or blonde hair association with pigmentary glaucoma in Israel

Levy, Yair; Glovinsky, Yoseph

doi:10.1038/sj.eye.6700007

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Cited by 4 publications

(1 citation statement)

References 14 publications

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“…We took advantage of the fact that red hair cosegregated with the disease and showed that in these patients the two loci are located very close to each other. Of note, in another study from Israel, Levy and Glovinsky 18 found an association between red and blonde hair color and pigmentary glaucoma (PG). Nineteen of 35 patients with PG had red or blonde hair compared with only 16 with black hair.…”

Section: Discussionmentioning

confidence: 99%

Mapping of a Gene Causing Brittle Cornea Syndrome in Tunisian Jews to 16q24

Abu

Frydman

Marek

et al. 2006

Invest. Ophthalmol. Vis. Sci.

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Section: Discussionmentioning

confidence: 99%

Mapping of a Gene Causing Brittle Cornea Syndrome in Tunisian Jews to 16q24

Abu

Frydman

Marek

et al. 2006

Invest. Ophthalmol. Vis. Sci.

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What is the connection between red hair and Tourette syndrome?

Sterling-Levis

Williams

2009

Medical Hypotheses

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Complex Genetics of Glaucoma Susceptibility

Libby

Gould

Anderson

et al. 2005

Annu. Rev. Genom. Hum. Genet.

155

131

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Glaucoma describes a group of diseases that kill retinal ganglion cells. There are different types of glaucoma, and each appears to be genetically heterogeneous. Different glaucoma genes have been identified, but these genes account for only a small proportion of glaucoma. Most glaucoma cases appear to be multifactorial, and are likely affected by multiple interacting loci. A number of genetic susceptibility factors have been suggested to contribute to glaucoma. These factors fit into two broad groups, those affecting intraocular pressure and those important in modulating retinal ganglion cell viability. Defining the complex genetics of glaucoma will require significant further study of the human disease and animal models. Genetic approaches are essential and will be enhanced by recently developed genomic and proteomic technologies. These technologies will provide valuable clues about pathogenesis for subsequent testing. In this review, we focus on endogenous genetic susceptibility factors and on how experimental studies will be valuable for dissecting the multifactorial complexity of their interactions.

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Red and/or blonde hair association with pigmentary glaucoma in Israel

Cited by 4 publications

References 14 publications

Mapping of a Gene Causing Brittle Cornea Syndrome in Tunisian Jews to 16q24

Mapping of a Gene Causing Brittle Cornea Syndrome in Tunisian Jews to 16q24

What is the connection between red hair and Tourette syndrome?

Complex Genetics of Glaucoma Susceptibility

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